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Can Urol Assoc J. 2014 May;8(5):E361-3. doi: 10.5489/cuaj.1692.

Isolated anterior urethral recurrence of prostatic adenocarcinoma.

Canadian Urological Association journal = Journal de l'Association des urologues du Canada

Darren Beiko, Khaled Zaza, Kevin V Power, D Robert Siemens, Alexander H Boag

Affiliations

  1. Department of Urology, Queen's University, Kingston General Hospital, Kingston, ON;
  2. Division of Radiation Oncology, Queen's University, Kingston General Hospital, Kingston, ON;
  3. Division of Urology, Department of Surgery, Queensway Carleton Hospital, Ottawa, ON.
  4. Department of Pathology, Queen's University, Kingston General Hospital, Kingston, ON;

PMID: 24940466 PMCID: PMC4039603 DOI: 10.5489/cuaj.1692

Abstract

Isolated anterior urethral metastases from prostate cancer are rare. The pathogenesis of this form of loco-regional recurrence may be related to spread by instrumentation-induced implantation and could potentially then be associated with a better prognosis than metastatic disease secondary to a more malignant phenotype. We report a case of a 68-year-old man with high-risk prostate cancer, diagnosed at transurethral resection of prostate, who was originally treated with combination external beam radiotherapy and hormonal therapy. He re-presented 4 years after his original diagnosis with recurrent gross hematuria and cystourethroscopic biopsies of anterior urethral polyps revealing isolated recurrent prostatic adenocarcinoma. We present our this case and review the literature.

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