Display options
Cite
Kojima S, Hoso M, Watanabe M, et al. Experimental joint immobilization and remobilization in the rats. J Phys Ther Sci. 2014;26(6):865-71doi: 10.1589/jpts.26.865.
Kojima, S., Hoso, M., Watanabe, M., Matsuzaki, T., Hibino, I., & Sasaki, K. (2014). Experimental joint immobilization and remobilization in the rats. Journal of physical therapy science, 26(6), 865-71. https://doi.org/10.1589/jpts.26.865
Kojima, Satoshi, et al. "Experimental joint immobilization and remobilization in the rats." Journal of physical therapy science vol. 26,6 (2014): 865-71. doi: https://doi.org/10.1589/jpts.26.865
Kojima S, Hoso M, Watanabe M, Matsuzaki T, Hibino I, Sasaki K. Experimental joint immobilization and remobilization in the rats. J Phys Ther Sci. 2014 Jun;26(6):865-71. doi: 10.1589/jpts.26.865. Epub 2014 Jun 30. PMID: 25013285; PMCID: PMC4085210.
Copy Download .nbib Format: NLM
Share it on

J Phys Ther Sci. 2014 Jun;26(6):865-71. doi: 10.1589/jpts.26.865. Epub 2014 Jun 30.

Experimental joint immobilization and remobilization in the rats.

Journal of physical therapy science

Satoshi Kojima, Masahiro Hoso, Masanori Watanabe, Taro Matsuzaki, Itaru Hibino, Kentaro Sasaki

Affiliations

  1. Department of Physical Therapy, Faculty of Health Sciences, Kinjo University, Japan ; Division of Health Sciences, Graduate School of Medical Science, Kanazawa University, Japan.
  2. Division of Health Sciences, Graduate School of Medical Science, Kanazawa University, Japan.
  3. Department of Physical Therapy, Faculty of Rehabilitation Sciences, Nagoya Gakuin University, Japan.
  4. Department of Physical Therapy, Faculty of Health Sciences, Kinjo University, Japan.

PMID: 25013285 PMCID: PMC4085210 DOI: 10.1589/jpts.26.865

Abstract

[Purpose] The purpose of our study was to clarify temporal effects on restrictions to range of motion and the histopathological changes of joint components after joint immobilization in a rat knee-contracture model. [Subjects] Fifty-four male Wistar rats were randomly divided into two groups: a fixation group, and a control group. [Methods] In the fixation group, unilateral knee joints were immobilized at full flexion using a plaster cast for 4 weeks. At four weeks the animals were randomly divided into six subgroups, corresponding to the time of examination after cast removal: 0, 4, 8, 16, 24, and 32 weeks. For comparison, control group animals of corresponding age were also examined. [Results] Although movement restrictions of the knee joint had completely recovered 6 weeks after the cast removal, cartilage and synovial membrane structures did not completely recover. [Conclusion] These findings have not previously been reported, and as they form an addition to the fundamental scientific foundations of physical therapy, further research must examine these findings from a variety of perspectives.

Keywords: Articular cartilage; Contracture; Synovial membrane

References

  1. Nihon Seikeigeka Gakkai Zasshi. 1966 Jul;40(4):431-53 - PubMed
  2. Arch Phys Med Rehabil. 2000 Jan;81(1):6-13 - PubMed
  3. Osteoarthritis Cartilage. 2006 Jan;14(1):13-29 - PubMed
  4. J Bone Joint Surg Am. 1971 Apr;53(3):523-37 - PubMed
  5. J Orthop Res. 2009 Feb;27(2):236-42 - PubMed
  6. Pathologe. 2006 Nov;27(6):431-8 - PubMed

Publication Types