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Oncol Lett. 2014 Aug;8(2):908-910. doi: 10.3892/ol.2014.2185. Epub 2014 May 27.

Simultaneous occurrence of two B-cell malignancies: A case report.

Oncology letters

Shujuan Zhou, Yongyong Ma, Laixi Bi, Zhijian Shen, Kang Yu

Affiliations

  1. Department of Hematology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, P.R. China.

PMID: 25013515 PMCID: PMC4081405 DOI: 10.3892/ol.2014.2185

Abstract

The present study describes the case of a 75-year-old male with coexisting multiple myeloma and diffuse large B-cell lymphoma. Although the two malignancies are mature B-cell neoplasms, their clinical manifestations are very different and the clinical approaches used to treat these two types of tumor vary. The patient in the present case was diagnosed with the simultaneous existence of two different B-cell tumors and was successfully treated using the DCEP regimen. The simultaneous presentation of two mature B-cell neoplasms, types of hematological malignancy, is very rare, thus the present case is considered to be interesting.

Keywords: DCEP regimen; diffuse large B-cell lymphoma; double B-cell malignancies; multiple myeloma

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