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Pandya AN, Agrawal DK. A concise synthesis of highly substituted imidazoles via copper-mediated oxidative C-H functionalization. Tetrahedron Lett. 2014;55(10):1835-1838doi: 10.1016/j.tetlet.2014.01.136.
Pandya, A. N., & Agrawal, D. K. (2014). A concise synthesis of highly substituted imidazoles via copper-mediated oxidative C-H functionalization. Tetrahedron letters, 55(10), 1835-1838. https://doi.org/10.1016/j.tetlet.2014.01.136
Pandya, Amit N, and Agrawal, Devendra K. "A concise synthesis of highly substituted imidazoles via copper-mediated oxidative C-H functionalization." Tetrahedron letters vol. 55,10 (2014): 1835-1838. doi: https://doi.org/10.1016/j.tetlet.2014.01.136
Pandya AN, Agrawal DK. A concise synthesis of highly substituted imidazoles via copper-mediated oxidative C-H functionalization. Tetrahedron Lett. 2014 Mar 05;55(10):1835-1838. doi: 10.1016/j.tetlet.2014.01.136. PMID: 24882889; PMCID: PMC4034134.
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Tetrahedron Lett. 2014 Mar 05;55(10):1835-1838. doi: 10.1016/j.tetlet.2014.01.136.

A concise synthesis of highly substituted imidazoles via copper-mediated oxidative C-H functionalization.

Tetrahedron letters

Amit N Pandya, Devendra K Agrawal

Affiliations

  1. Department of Biomedical Sciences, Creighton University School of Medicine, Omaha, NE 68178, USA.
  2. Department of Biomedical Sciences, Creighton University School of Medicine, Omaha, NE 68178, USA ; Center for Clinical and Translational Science, Creighton University School of Medicine, Omaha, NE 68178, USA.

PMID: 24882889 PMCID: PMC4034134 DOI: 10.1016/j.tetlet.2014.01.136

Abstract

We herein report a simple and concise route for the synthesis of highly substituted imidazole derivatives via copper-mediated oxidative C-H functionalization in good to high yields. The advantage of the reaction lies in its mild reaction conditions and readily available starting materials.

Keywords: C–H functionalization; Imidazole; Oxidative dehydrogenation

References

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