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Vakili B, Fazeli H, Shoaei P, et al. Detection of colistin sensitivity in clinical isolates of Acinetobacter baumannii in Iran. J Res Med Sci. 2014;19:S67-70
Vakili, B., Fazeli, H., Shoaei, P., Yaran, M., Ataei, B., Khorvash, F., & Khaleghi, M. (2014). Detection of colistin sensitivity in clinical isolates of Acinetobacter baumannii in Iran. Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences, 19S67-70.
Vakili, Bahareh, et al. "Detection of colistin sensitivity in clinical isolates of Acinetobacter baumannii in Iran." Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences vol. 19 (2014): S67-70.
Vakili B, Fazeli H, Shoaei P, Yaran M, Ataei B, Khorvash F, Khaleghi M. Detection of colistin sensitivity in clinical isolates of Acinetobacter baumannii in Iran. J Res Med Sci. 2014 Mar;19:S67-70. PMID: 25002899; PMCID: PMC4078383.
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J Res Med Sci. 2014 Mar;19:S67-70.

Detection of colistin sensitivity in clinical isolates of Acinetobacter baumannii in Iran.

Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences

Bahareh Vakili, Hossein Fazeli, Parisa Shoaei, Majid Yaran, Behrooz Ataei, Farzin Khorvash, Moj Khaleghi

Affiliations

  1. Department of Microbiology, Science and Research Branch, Islami Azad University, Kerman, Iran.
  2. Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
  3. Nosocomial Infection Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
  4. Acquired Immunodeficiency Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
  5. Department of Biology, Faculty of Science, Shahid Bahonar University of Kerman, Iran.

PMID: 25002899 PMCID: PMC4078383

Abstract

BACKGROUND: Nosocomial infection caused by Acinetobacter baumannii has emerged as a serious problem world-wide. Finding the suitable drug is an important priority. The aim of this study was to determine colistin (polymyxin E) resistance in clinical isolates of A. baumannii from intensive care units (ICUs) of Al Zahra Hospital.

MATERIALS AND METHODS: Sixty isolates of A. baumannii from patients hospitalized in ICU (Al Zahra Hospital, Isfahan University of Medical Sciences [IUMS]) were studied. All isolates of A. baumannii were tested for colistin susceptibility by Eopsilometer test (E-test).

RESULTS: Of the 60 isolates 57, (95%) were multidrug resistant (MDR) and 76.6% (46/60) were highly resistant. The rate of colistin resistant with the E-test method was 11.6% (7/60).

CONCLUSION: As the frequency of resistance to colistin is low, it can be used as an easily available drug for treatment of MDR A. baumannii strains, which are susceptible to colistin.

Keywords: Acinetobacter baumannii; colistin resistance; multidrug resistant organism

References

  1. J Clin Microbiol. 2007 Oct;45(10):3352-9 - PubMed
  2. Chemotherapy. 2010;56(6):478-84 - PubMed
  3. Infect Control Hosp Epidemiol. 1997 Jul;18(7):499-503 - PubMed
  4. Crit Care. 2003 Oct;7(5):R78-83 - PubMed
  5. Eur J Cardiothorac Surg. 2008 Jun;33(6):1086-90 - PubMed
  6. J Antimicrob Chemother. 2007 Mar;59(3):473-7 - PubMed
  7. J Antimicrob Chemother. 2012 Jul;67(7):1607-15 - PubMed
  8. Antimicrob Agents Chemother. 2009 Mar;53(3):1295-6 - PubMed
  9. J Clin Microbiol. 2005 Feb;43(2):903-5 - PubMed
  10. Clin Infect Dis. 2000 Jul;31(1):101-6 - PubMed
  11. Ann Pharmacother. 2004 Sep;38(9):1449-59 - PubMed
  12. Acta Med Iran. 2010 May-Jun;48(3):178-84 - PubMed
  13. BMC Infect Dis. 2010 Jul 07;10:196 - PubMed
  14. Int J Infect Dis. 2009 Sep;13(5):e217-20 - PubMed
  15. J Antimicrob Chemother. 2007 Nov;60(5):1163-7 - PubMed

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