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Int J Womens Health. 2014 Jun 23;6:631-7. doi: 10.2147/IJWH.S46680. eCollection 2014.

Menstrual suppression: current perspectives.

International journal of women's health

Paula Adams Hillard

Affiliations

  1. Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, CA, USA.

PMID: 25018654 PMCID: PMC4075955 DOI: 10.2147/IJWH.S46680

Abstract

Menstrual suppression to provide relief of menstrual-related symptoms or to manage medical conditions associated with menstrual morbidity or menstrual exacerbation has been used clinically since the development of steroid hormonal therapies. Options range from the extended or continuous use of combined hormonal oral contraceptives, to the use of combined hormonal patches and rings, progestins given in a variety of formulations from intramuscular injection to oral therapies to intrauterine devices, and other agents such as gonadotropin-releasing hormone (GnRH) antagonists. The agents used for menstrual suppression have variable rates of success in inducing amenorrhea, but typically have increasing rates of amenorrhea over time. Therapy may be limited by side effects, most commonly irregular, unscheduled bleeding. These therapies can benefit women's quality of life, and by stabilizing the hormonal milieu, potentially improve the course of underlying medical conditions such as diabetes or a seizure disorder. This review addresses situations in which menstrual suppression may be of benefit, and lists options which have been successful in inducing medical amenorrhea.

Keywords: amenorrhea; inducing amenorrhea; menstrual molimena; quality of life

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