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Bhargava R, Hahn G, Hirsch W, et al. Contrast-enhanced magnetic resonance imaging in pediatric patients: review and recommendations for current practice. Magn Reson Insights. 2013;6:95-111doi: 10.4137/MRI.S12561.
Bhargava, R., Hahn, G., Hirsch, W., Kim, M. J., Mentzel, H. J., Olsen, O. E., Stokland, E., Triulzi, F., & Vazquez, E. (2013). Contrast-enhanced magnetic resonance imaging in pediatric patients: review and recommendations for current practice. Magnetic resonance insights, 695-111. https://doi.org/10.4137/MRI.S12561
Bhargava, Ravi, et al. "Contrast-enhanced magnetic resonance imaging in pediatric patients: review and recommendations for current practice." Magnetic resonance insights vol. 6 (2013): 95-111. doi: https://doi.org/10.4137/MRI.S12561
Bhargava R, Hahn G, Hirsch W, Kim MJ, Mentzel HJ, Olsen OE, Stokland E, Triulzi F, Vazquez E. Contrast-enhanced magnetic resonance imaging in pediatric patients: review and recommendations for current practice. Magn Reson Insights. 2013 Oct 20;6:95-111. doi: 10.4137/MRI.S12561. eCollection 2013. PMID: 25114547; PMCID: PMC4089734.
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Magn Reson Insights. 2013 Oct 20;6:95-111. doi: 10.4137/MRI.S12561. eCollection 2013.

Contrast-enhanced magnetic resonance imaging in pediatric patients: review and recommendations for current practice.

Magnetic resonance insights

Ravi Bhargava, Gabriele Hahn, Wolfgang Hirsch, Myung-Joon Kim, Hans-Joachim Mentzel, Oystein E Olsen, Eira Stokland, Fabio Triulzi, Elida Vazquez

Affiliations

  1. Division of Pediatric Radiology, Department of Radiology and Diagnostic Imaging, Stollery Children's Hospital, University of Alberta, Edmonton, Alberta, Canada.
  2. Institut und Poliklinik für Radiologische Diagnostik, Universitätsklinikum Carl Gustav Carus, Dresden, Germany.
  3. Department of Paediatric Radiology, University of Leipzig, Germany.
  4. Department of Diagnostic Radiology, Yonsei University College of Medicine, Seoul, South Korea.
  5. Department of Pediatric Radiology, Jena University Hospital, Jena, Germany.
  6. Radiology Department, Great Ormond Street Hospital for Children NHS Trust, London, UK.
  7. Department of Paediatric Radiology, Sahlgrenska University Hospital, Gothenburg, Sweden.
  8. Department of Radiology and Neuroradiology, Ospedale Vittore Buzzi Pediatric Hospital, Milan, Italy.
  9. Radiology Department, Hospital Materno-Infantil Vall d'Hebron, Barcelona, Spain.

PMID: 25114547 PMCID: PMC4089734 DOI: 10.4137/MRI.S12561

Abstract

Magnetic resonance imaging (MRI), frequently with contrast enhancement, is the preferred imaging modality for many indications in children. Practice varies widely between centers, reflecting the rapid pace of change and the need for further research. Guide-line changes, for example on contrast-medium choice, require continued practice reappraisal. This article reviews recent developments in pediatric contrast-enhanced MRI and offers recommendations on current best practice. Nine leading pediatric radiologists from internationally recognized radiology centers convened at a consensus meeting in Bordeaux, France, to discuss applications of contrast-enhanced MRI across a range of indications in children. Review of the literature indicated that few published data provide guidance on best practice in pediatric MRI. Discussion among the experts concluded that MRI is preferred over ionizing-radiation modalities for many indications, with advantages in safety and efficacy. Awareness of age-specific adaptations in MRI technique can optimize image quality. Gadolinium-based contrast media are recommended for enhancing imaging quality. The choice of most appropriate contrast medium should be based on criteria of safety, tolerability, and efficacy, characterized in age-specific clinical trials and personal experience.

Keywords: contrast-enhanced; expert consensus; gadobutrol; gadolinium; magnetic resonance imaging; pediatrics

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