Display options
Share it on

Can Urol Assoc J. 2014 May;8(5):E468-70. doi: 10.5489/cuaj.1876.

Secondary sarcoma of bone post-prostate brachytherapy: A case report.

Canadian Urological Association journal = Journal de l'Association des urologues du Canada

Allison Y Ye, Jessica Conway, Michael Peacock, Paul W Clarkson, Cheng-Han Lee, Christine Simmons, Lorna Weir, Michael McKenzie

Affiliations

  1. Department of Radiation Oncology, Vancouver Cancer Centre, British Columbia Cancer Agency, Vancouver, BC;
  2. Department of Orthopedics, University of British Columbia, Vancouver, BC;
  3. Department of Laboratory Medicine and Pathology, University of Alberta and Royal Alexandra Hospital, Edmonton, AB;
  4. Department of Medical Oncology, Vancouver Cancer Centre, British Columbia Cancer Agency, Vancouver, BC.

PMID: 25024811 PMCID: PMC4081272 DOI: 10.5489/cuaj.1876

Abstract

Malignancies associated with brachytherapy for prostate cancer are largely unreported in the literature. We report a case of post-brachytherapy osteogenic sarcoma in the pelvis 6 years after permanent (125)I implant for intermediate-risk prostate cancer. The patient was treated with neoadjuvant chemotherapy, limb-sparing surgical resection and postoperative radiation therapy for unexpected positive margins.

References

  1. Urology. 1999 Jun;53(6):1228 - PubMed
  2. Ann ICRP. 2007;37(2-4):1-332 - PubMed
  3. Radiat Environ Biophys. 2008 Feb;47(1):39-47 - PubMed
  4. Cancer. 2000 Jan 15;88(2):398-406 - PubMed
  5. Brachytherapy. 2012 Sep-Oct;11(5):354-8 - PubMed
  6. Acta Oncol. 2013 Aug;52(6):1215-6 - PubMed
  7. Crit Rev Oncol Hematol. 2012 Sep;83(3):393-406 - PubMed
  8. Scand J Urol Nephrol. 2011 Nov;45(5):356-8 - PubMed
  9. J Clin Oncol. 2011 Dec 1;29(34):4510-5 - PubMed
  10. Int J Radiat Oncol Biol Phys. 2008 Sep 1;72(1):58-68 - PubMed
  11. J Urol. 2003 Jan;169(1):280 - PubMed
  12. Cancer. 2006 Sep 1;107(5):991-8 - PubMed

Publication Types