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World J Clin Cases. 2014 Jul 16;2(7):311-5. doi: 10.12998/wjcc.v2.i7.311.

Diagnostic pitfall of sebaceous gland metaplasia of the esophagus.

World journal of clinical cases

King-Wah Chiu, Cheng-Kun Wu, Long-Sheng Lu, Hock-Liew Eng, Shue-Shian Chiou

Affiliations

  1. King-Wah Chiu, Cheng-Kun Wu, Long-Sheng Lu, Shue-Shian Chiou, Department of Internal Medicine, Division of Gastroenterology and Hepatology, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University, College of Medicine, Kaohsiung 83305, Taiwan.

PMID: 25032211 PMCID: PMC4097163 DOI: 10.12998/wjcc.v2.i7.311

Abstract

We investigated the sebaceous gland metaplasia (SGM) of the esophagus and clarified the evidence of misdiagnosis and its diagnosis pitfall. Cases of pathologically proven SGM were enrolled in the clinical analysis and reviewed description of endoscope. In the current study, we demonstrated that SGM is very rare esophageal condition with an incidence around 0.00465% and an occurrence rate of 0.41 per year. There were 57.1% of senior endoscopists identified 8 episodes of SGM. In contrast, 7.7% of junior endoscopists identified SGM in only 2 episodes. Moreover, we investigated the difference in endoscopic biopsy attempt rate between the senior and junior endoscopist (P = 0.0001). The senior endoscopists had more motivation to look for SGM than did junior endoscopists (P = 0.01). We concluded that SGM of the esophagus is rare condition that is easily and not recognized in endoscopy studies omitting pathological review.

Keywords: Endoscopist; Endoscopy; Esophagus; Metaplasia; Sebaceous gland

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