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Surg Neurol Int. 2014 Jun 30;5:103. doi: 10.4103/2152-7806.135579. eCollection 2014.

Neurogenic pulmonary edema caused by spontaneous cerebellar hemorrhage: A fatal case report.

Surgical neurology international

Qiaoding Dai, Lida Su

Affiliations

  1. Department of Rheumatism and Immunology, the First Affiliated Hospital of Zhejiang Chinese Medicine University, Hangzhou City, Zhejiang Province, PR, China.
  2. Neuroscience Care Unit, Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou City, Zhejiang Province, PR, China.

PMID: 25101198 PMCID: PMC4123267 DOI: 10.4103/2152-7806.135579

Abstract

BACKGROUND: Neurogenic pulmonary edema (NPE) is a clinical syndrome characterized by an acute increase of pulmonary interstitial and alveolar fluid. It could result from a significant central nervous system (CNS) insult such as intracranial hemorrhage. However, NPE as a major presenting manifestation of cerebellar hemorrhage was seldom reported.

CASE DESCRIPTION: We introduce a rare case of a 34-year-old woman suffering from a fulminant NPE in parallel with a spontaneous cerebellar hemorrhage. Although appropriate supportive measures were taken in the neuroscience care unit, the patient failed to survive hypoxemia within 28 h after hospital admission.

CONCLUSION: Pathological lesions of the cerebellum may initiate a cascade of reactions including massive sympathetic discharge and catecholamine storm, leading to a dysfunction of both cardiovascular and respiratory systems. By far, no effective therapeutic strategies have been utilized to treat such a situation. Our present report would shed light on the underlying mechanism of NPE.

Keywords: Respiratory dysfunction; neurogenic pulmonary edema; spontaneous cerebellar hemorrhage

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