Surg Neurol Int. 2014 Jun 30;5:103. doi: 10.4103/2152-7806.135579. eCollection 2014.
Neurogenic pulmonary edema caused by spontaneous cerebellar hemorrhage: A fatal case report.
Surgical neurology international
Qiaoding Dai, Lida Su
Affiliations
Affiliations
- Department of Rheumatism and Immunology, the First Affiliated Hospital of Zhejiang Chinese Medicine University, Hangzhou City, Zhejiang Province, PR, China.
- Neuroscience Care Unit, Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou City, Zhejiang Province, PR, China.
PMID: 25101198
PMCID: PMC4123267 DOI: 10.4103/2152-7806.135579
Abstract
BACKGROUND: Neurogenic pulmonary edema (NPE) is a clinical syndrome characterized by an acute increase of pulmonary interstitial and alveolar fluid. It could result from a significant central nervous system (CNS) insult such as intracranial hemorrhage. However, NPE as a major presenting manifestation of cerebellar hemorrhage was seldom reported.
CASE DESCRIPTION: We introduce a rare case of a 34-year-old woman suffering from a fulminant NPE in parallel with a spontaneous cerebellar hemorrhage. Although appropriate supportive measures were taken in the neuroscience care unit, the patient failed to survive hypoxemia within 28 h after hospital admission.
CONCLUSION: Pathological lesions of the cerebellum may initiate a cascade of reactions including massive sympathetic discharge and catecholamine storm, leading to a dysfunction of both cardiovascular and respiratory systems. By far, no effective therapeutic strategies have been utilized to treat such a situation. Our present report would shed light on the underlying mechanism of NPE.
Keywords: Respiratory dysfunction; neurogenic pulmonary edema; spontaneous cerebellar hemorrhage
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