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Leon B, Miller BV, Zalos G, et al. Weight Loss Programs May Have Beneficial or Adverse Effects on Fat Mass and Insulin Sensitivity in Overweight and Obese Black Women. J Racial Ethn Health Disparities. 2014;1:140-147doi: 10.1007/s40615-014-0006-6.
Leon, B., Miller, B. V., Zalos, G., Courville, A. B., Sumner, A. E., Powell-Wiley, T. M., Walter, M. F., Waclawiw, M. A., & Cannon, R. O. (2014). Weight Loss Programs May Have Beneficial or Adverse Effects on Fat Mass and Insulin Sensitivity in Overweight and Obese Black Women. Journal of racial and ethnic health disparities, 1140-147. https://doi.org/10.1007/s40615-014-0006-6
Leon, Benjamin, et al. "Weight Loss Programs May Have Beneficial or Adverse Effects on Fat Mass and Insulin Sensitivity in Overweight and Obese Black Women." Journal of racial and ethnic health disparities vol. 1 (2014): 140-147. doi: https://doi.org/10.1007/s40615-014-0006-6
Leon B, Miller BV, Zalos G, Courville AB, Sumner AE, Powell-Wiley TM, Walter MF, Waclawiw MA, Cannon RO. Weight Loss Programs May Have Beneficial or Adverse Effects on Fat Mass and Insulin Sensitivity in Overweight and Obese Black Women. J Racial Ethn Health Disparities. 2014;1:140-147. doi: 10.1007/s40615-014-0006-6. Epub 2014 Mar 05. PMID: 25110634; PMCID: PMC4125812.
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J Racial Ethn Health Disparities. 2014;1:140-147. doi: 10.1007/s40615-014-0006-6. Epub 2014 Mar 05.

Weight Loss Programs May Have Beneficial or Adverse Effects on Fat Mass and Insulin Sensitivity in Overweight and Obese Black Women.

Journal of racial and ethnic health disparities

Benjamin Leon, Bernard V Miller, Gloria Zalos, Amber B Courville, Anne E Sumner, Tiffany M Powell-Wiley, Mary F Walter, Myron A Waclawiw, Richard O Cannon

Affiliations

  1. Cardiovascular and Pulmonary Branch, National Heart, Lung, and Blood Institute, Building 10-CRC Room 5-3330, 10 Center Drive, Bethesda, MD 20892 USA.
  2. Diabetes, Endocrinology and Obesity Branch, Clinical Center; National Institutes of Health, Bethesda, MD USA.
  3. Nutrition Department, Clinical Center; National Institutes of Health, Bethesda, MD USA.
  4. Core for Clinical Laboratory Services, Clinical Center; National Institutes of Health, Bethesda, MD USA.
  5. Office of Biostatistics Research, National Heart, Lung, and Blood Institute, Bethesda, MD USA.

PMID: 25110634 PMCID: PMC4125812 DOI: 10.1007/s40615-014-0006-6

Abstract

OBJECTIVE: Weight loss interventions have produced little change in insulin sensitivity in black women, but mean data may obscure metabolic benefit to some and adverse effects for others. Accordingly, we analyzed insulin sensitivity relative to fat mass change following a weight loss program.

DESIGN AND METHODS: Fifty-four black women (BMI range 25.9 to 54.7 kg/m

RESULTS: Baseline S

CONCLUSIONS: Black women in a weight loss program who lose fat mass may have improved insulin sensitivity, but fat mass gain with diminished sensitivity is common. Additional support for participants who fail to achieve fat mass loss early in an intervention may be required for success.

Keywords: Obesity; insulin sensitivity; intervention; race; women

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