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Zhang J, Zhou S, Xu G. Carotid baroreceptor stimulation: a potential solution for resistant hypertension. Interv Neurol. 2014;2(3):118-22doi: 10.1159/000357167.
Zhang, J., Zhou, S., & Xu, G. (2014). Carotid baroreceptor stimulation: a potential solution for resistant hypertension. Interventional neurology, 2(3), 118-22. https://doi.org/10.1159/000357167
Zhang, Jun, et al. "Carotid baroreceptor stimulation: a potential solution for resistant hypertension." Interventional neurology vol. 2,3 (2014): 118-22. doi: https://doi.org/10.1159/000357167
Zhang J, Zhou S, Xu G. Carotid baroreceptor stimulation: a potential solution for resistant hypertension. Interv Neurol. 2014 May;2(3):118-22. doi: 10.1159/000357167. PMID: 25187787; PMCID: PMC4062316.
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Interv Neurol. 2014 May;2(3):118-22. doi: 10.1159/000357167.

Carotid baroreceptor stimulation: a potential solution for resistant hypertension.

Interventional neurology

Jun Zhang, Shuyu Zhou, Gelin Xu

Affiliations

  1. Department of Neurology, Jinling Hospital, Nanjing University School of Medicine, Southern Medical University, Nanjing, China.
  2. Department of Neurology, Jinling Hospital, Nanjing University School of Medicine, Southern Medical University, Nanjing, China ; Department of Neurology, Jinling Hospital, Southern Medical University, Nanjing, China.

PMID: 25187787 PMCID: PMC4062316 DOI: 10.1159/000357167

Abstract

Resistant hypertension indicates that the blood pressure cannot reach the target value despite standard drug treatment, which harbors an increased risk for cardiovascular diseases. The role of the carotid sinus in regulating blood pressure has long been observed; thereby, the idea that treating resistant hypertension by stimulating carotid baroreceptors emerged. Nevertheless, this idea has been abandoned for years due to technical limitations. Recently, with the evolutions in implantable electrical devices, expectations for treating resistant hypertension with baroreceptor stimulation have increased. Positive results from several multicenter clinical trials further captured the researchers' enthusiasm for more effective baroreceptor-stimulating devices. This study reviews the recent progress in baroreceptor stimulation as a treatment alternative for resistant hypertension.

Keywords: Baroreceptor; Carotid sinus; Electrical stimulation; Resistant hypertension

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