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Kalayci TO, Erdem G, Kutlu R, et al. Diffusion-Weighted Magnetic Resonance Imaging and Magnetic Resonance Spectroscopy Features of Abdominal Viscera in a Patient with Gaucher's Disease. Malays J Med Sci. 2014;21(3):89-93
Kalayci, T. O., Erdem, G., Kutlu, R., Kahraman, A., & Alkan, A. (2014). Diffusion-Weighted Magnetic Resonance Imaging and Magnetic Resonance Spectroscopy Features of Abdominal Viscera in a Patient with Gaucher's Disease. The Malaysian journal of medical sciences : MJMS, 21(3), 89-93.
Kalayci, Tugce Ozlem, et al. "Diffusion-Weighted Magnetic Resonance Imaging and Magnetic Resonance Spectroscopy Features of Abdominal Viscera in a Patient with Gaucher's Disease." The Malaysian journal of medical sciences : MJMS vol. 21,3 (2014): 89-93.
Kalayci TO, Erdem G, Kutlu R, Kahraman A, Alkan A. Diffusion-Weighted Magnetic Resonance Imaging and Magnetic Resonance Spectroscopy Features of Abdominal Viscera in a Patient with Gaucher's Disease. Malays J Med Sci. 2014 May;21(3):89-93. PMID: 25246842; PMCID: PMC4163565.
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Malays J Med Sci. 2014 May;21(3):89-93.

Diffusion-Weighted Magnetic Resonance Imaging and Magnetic Resonance Spectroscopy Features of Abdominal Viscera in a Patient with Gaucher's Disease.

The Malaysian journal of medical sciences : MJMS

Tugce Ozlem Kalayci, Gulnur Erdem, Ramazan Kutlu, Aysegül Kahraman, Alpay Alkan

Affiliations

  1. Inonu University, Medical Faculty, Department of Radiology, 44100, Malatya, Turkey.

PMID: 25246842 PMCID: PMC4163565

Abstract

A 46-year-old woman with Gaucher's disease (GD) consulted our clinic for abdominopelvic magnetic resonance imaging (MRI), as physical examination had revealed hepatosplenomegaly. Upper abdominal MRI showed massive hepatosplenomegaly and innumerable hypointense splenic nodules on T1-weighted images. Diffusion-weighted MRI (DW-MRI) and magnetic resonance spectroscopy (MRS) were performed to liver parenchyma and splenic nodules. MRS revealed lactate, lipid, acetate, and alanine peaks in splenic nodules, and choline, creatine, lipid, myo-inositol-glycine, and lactate peaks in the liver parenchyma. The DW-MRI showed diffusion restriction in splenic nodules. It was concluded that MRI is a reliable method for the diagnosis and follow up of GD. Coupling DW-MRI and MRS allows quantitative evaluation, thereby increasing the efficacy of the method. This is the first report in the literature presenting advanced abdominal MRI findings in GD.

Keywords: Gaucher disease; diffusion magnetic resonance imaging; magnetic resonance spectroscopy

References

  1. Neuroradiology. 2009 Nov;51(11):773-9 - PubMed
  2. AJR Am J Roentgenol. 2007 Jun;188(6):1622-35 - PubMed
  3. Diagn Interv Radiol. 2008 Jun;14(2):83-7 - PubMed
  4. AJR Am J Roentgenol. 1995 Sep;165(3):599-604 - PubMed
  5. Eur Radiol. 2008 Nov;18(11):2549-58 - PubMed
  6. Radiology. 1992 Aug;184(2):561-6 - PubMed
  7. Eur Radiol. 2013 Nov;23(11):3005-11 - PubMed
  8. Skeletal Radiol. 2013 Feb;42(2):283-7 - PubMed
  9. Abdom Imaging. 2000 May-Jun;25(3):286-9 - PubMed

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