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Boloursaz MR, Khalilzadeh S, Nezhad PR, et al. Chest CT Manifestations in Children with CVID: A 10-Year Report. Tanaffos. 2012;11(4):56-9
Boloursaz, M. R., Khalilzadeh, S., Nezhad, P. R., Karam, M. B., Mahdaviani, A., Mosadegh, L., Hassanzad, M., & Hosseini, S. M. (2012). Chest CT Manifestations in Children with CVID: A 10-Year Report. Tanaffos, 11(4), 56-9.
Boloursaz, Mohammad Reza, et al. "Chest CT Manifestations in Children with CVID: A 10-Year Report." Tanaffos vol. 11,4 (2012): 56-9.
Boloursaz MR, Khalilzadeh S, Nezhad PR, Karam MB, Mahdaviani A, Mosadegh L, Hassanzad M, Hosseini SM. Chest CT Manifestations in Children with CVID: A 10-Year Report. Tanaffos. 2012;11(4):56-9. PMID: 25191439; PMCID: PMC4153219.
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Tanaffos. 2012;11(4):56-9.

Chest CT Manifestations in Children with CVID: A 10-Year Report.

Tanaffos

Mohammad Reza Boloursaz, Soheila Khalilzadeh, Pegah Rahmati Nezhad, Mehrdad Bakhshayesh Karam, Alireza Mahdaviani, Leila Mosadegh, Maryam Hassanzad, Seyed Mohsen Mir Hosseini

Affiliations

  1. Pediatric Respiratory Diseases Research Center, NRITLD, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  2. Chronic Respiratory Diseases Research Center, NRITLD, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

PMID: 25191439 PMCID: PMC4153219

Abstract

BACKGROUND: This study aimed at evaluating HRCT pulmonary manifestations in children with Common Variable Immunodeficiency (CVID) hospitalized in the Pediatric Ward of Masih Daneshvari Hospital during a 10-year period.

MATERIALS AND METHODS: This retrospective study evaluated 25 children hospitalized with the diagnosis of CVID in the Pediatric Ward of Masih Daneshvari Hospital from 2001 to 2011 and their pulmonary HRCT scans were evaluated.

RESULTS: The most common pulmonary HRCT findings were lymphadenopathy (66.7%), bronchiectasis (50%), air trapping (33.3%) and peribronchial wall thickening (33.3%). The highest percentage of CT-scan findings was detected in patients aged 13-17 yrs.

CONCLUSION: Most of the pulmonary changes due to CVID are preventable or treatable. Also, it is possible to prevent irreversible complications of disease if it is diagnosed early. Therefore, HRCT is strongly recommended as an accurate and effective method for monitoring and fast recognition of pulmonary manifestations of the disease especially bronchiectasis which is a very common finding indicative of poor prognosis.

Keywords: CT scan; Common variable immunodeficiency (CVID); HRCT

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