J Dent (Shiraz). 2014 Sep;15(3):123-8.
Effect of Oral Midazolam Premedication on Children's Co-operation Before General Anesthesia in Pediatric Dentistry.
Journal of dentistry (Shiraz, Iran)
Nasser Kaviani, Mina Shahtusi, Maryam Haj Norousali Tehrani, Sara Nazari
Affiliations
Affiliations
- MS. Anesthesiologist, Dept. of Oral and Maxillofacial Surgery, Torabinejad Dental Research Center, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.
- Postgraduate Student of Pediatrics, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.
- Dept. of Pediatric Dentistry, Torabinejad Dental Research Center, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.
- Dentist, Isfahan, Iran.
PMID: 25191661
PMCID: PMC4149894
Abstract
STATEMENT OF THE PROBLEM: Premedication is expedient in reducing the psychological trauma from recalling the unpleasant pre-anesthetic phases, hence, inducing a trouble-free anesthesia.
PURPOSE: This study aimed to determine the effectiveness of oral midazolam in co-operation of the subjects before general anesthesia and in recalling the pre-anesthetic phases, performed on children candidate for dental treatment under general anesthesia.
MATERIALS AND METHOD: In this prospective clinical trial study, 62 healthy non-cooperative children, candidate for dental treatment under general anesthesia, were randomly divided into study and control groups. The children received 20ml orange juice, 20 minutes before starting the anesthesia. The juice of the test group contained 0.5mg/kg of midazolam and that of the control group included no medication. The induction and the maintenance process of anesthesia were similar in both groups. The manner of subjects when separated from parents, their cooperation during intravenous catheterization, and recalling the pre-anesthetic events were recorded. Data were analyzed by adopting chi-square and Mann-Whitney tests.
RESULTS: Most of the children in the test group had a comfortable separation from parents, restful IV catheterization and 90% of the subjects did not recall the pre-anesthetic events.
CONCLUSION: Under the circumstances of this study, it could be concluded that 0.5mg/kg oral midazolam premedication is effective for comfortable separation of children from parents and restful IV catheterization and also forgetting the pre-anesthetic events.
Keywords: General anesthesia; Midazolam; Pediatric dentistry; Premedication
References
- Paediatr Anaesth. 2003 Mar;13(3):188-204 - PubMed
- Oral Maxillofac Surg Clin North Am. 2010 Nov;22(4):461-9 - PubMed
- Minerva Anestesiol. 2002 Jul-Aug;68(7-8):593-8 - PubMed
- Pediatr Dent. 2011 Jul-Aug;33(4):321-6 - PubMed
- J Oral Maxillofac Surg. 1997 Dec;55(12):1372-7; discussion 1378-9 - PubMed
- Saudi J Anaesth. 2012 Jan;6(1):8-11 - PubMed
- Pediatr Dent. 2010 Jul-Aug;32(4):289-94 - PubMed
- Anaesthesia. 2007 Aug;62(8):778-89 - PubMed
- Dent Update. 1997 Nov;24(9):376-81 - PubMed
- Anesthesiology. 1985 Mar;62(3):310-24 - PubMed
- Int J Pediatr. 2009;2009:274380 - PubMed
- Can J Anaesth. 1993 Aug;40(8):726-9 - PubMed
- Anesthesiology. 1990 Nov;73(5):831-4 - PubMed
- Paediatr Anaesth. 2009 Aug;19(8):748-55 - PubMed
- Paediatr Anaesth. 2006 Jul;16(7):748-53 - PubMed
- Anesth Analg. 2002 Jan;94(1):37-43, table of contents - PubMed
- Int J Paediatr Dent. 2001 Jan;11(1):33-40 - PubMed
- Eur J Anaesthesiol. 2011 Sep;28(9):640-5 - PubMed
- AANA J. 1995 Apr;63(2):124-30 - PubMed
- J Clin Anesth. 1995 Sep;7(6):500-6 - PubMed
- Pediatr Dent. 1997 Sep-Oct;19(6):427-31 - PubMed
- Can J Anaesth. 1992 Jul;39(6):545-50 - PubMed
- Br Dent J. 1997 Dec 13-27;183(11-12):399-407 - PubMed
- Pharmacogenet Genomics. 2011 Feb;21(2):84-93 - PubMed
- Anesth Analg. 2004 May;98(5):1252-9, table of contents - PubMed
- Eur J Anaesthesiol. 2010 Apr;27(4):341-6 - PubMed
- Pediatr Dent. 1993 Jul-Aug;15(4):237-41 - PubMed
- Anesth Analg. 1992 Jul;75(1):51-5 - PubMed
- AANA J. 2011 Jun;79(3):219-24 - PubMed
- Beijing Da Xue Xue Bao Yi Xue Ban. 2013 Dec 18;45(6):984-8 - PubMed
- Anesth Analg. 2004 Sep;99(3):833-839 - PubMed
- Can J Anaesth. 2006 Dec;53(12):1213-9 - PubMed
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