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Diaz JH, Roberts CA, Oliver JJ, et al. Propofol infusion syndrome or not? A case report. Ochsner J. 2014;14(3):434-7
Diaz, J. H., Roberts, C. A., Oliver, J. J., & Kaye, A. D. (2014). Propofol infusion syndrome or not? A case report. The Ochsner journal, 14(3), 434-7.
Diaz, James H, et al. "Propofol infusion syndrome or not? A case report." The Ochsner journal vol. 14,3 (2014): 434-7.
Diaz JH, Roberts CA, Oliver JJ, Kaye AD. Propofol infusion syndrome or not? A case report. Ochsner J. 2014;14(3):434-7. PMID: 25249811; PMCID: PMC4171803.
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Ochsner J. 2014;14(3):434-7.

Propofol infusion syndrome or not? A case report.

The Ochsner journal

James H Diaz, Cory A Roberts, Josh J Oliver, Alan David Kaye

Affiliations

  1. Department of Anesthesiology, Louisiana State University Health Sciences Center, New Orleans, LA ; School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA.
  2. School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA.
  3. Department of Anesthesiology, Louisiana State University Health Sciences Center, New Orleans, LA ; Department of Pharmacology, Louisiana State University Health Sciences Center, New Orleans, LA.

PMID: 25249811 PMCID: PMC4171803

Abstract

BACKGROUND: Propofol is commonly used and well tolerated for induction of general anesthesia and is also used as a sedative in the intensive care unit. However, in rare cases, the agent may cause a fatal condition known as propofol infusion syndrome (PRIS).

CASE REPORT: We present a case of PRIS that could have been fatal in a previously healthy male patient with multiple gunshot wounds.

CONCLUSION: Because patients typically exhibit other potentially fatal comorbidities, PRIS is always a diagnosis of exclusion. The true incidence of PRIS remains unknown, and more objective criteria for its diagnosis need to be established.

Keywords: Acidosis; acute kidney injury; hypnotics and sedatives; intensive care units; propofol; rhabdomyolysis; wounds–gunshot

References

  1. Neurology. 1998 Jan;50(1):301-3 - PubMed
  2. J Intensive Care Med. 2011 Mar-Apr;26(2):59-72 - PubMed
  3. BMJ. 1992 Sep 12;305(6854):613-6 - PubMed
  4. Paediatr Anaesth. 1998;8(6):491-9 - PubMed
  5. Crit Care. 2009;13(5):R169 - PubMed
  6. Anaesthesist. 2004 Oct;53(10):1009-22; quiz 1023-4 - PubMed
  7. Curr Opin Anaesthesiol. 2008 Oct;21(5):544-51 - PubMed
  8. Crit Care Med. 2008 Aug;36(8):2281-7 - PubMed
  9. Chest. 1996 Jan;109(1):292 - PubMed

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