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Mahmoud MA, Fahmy GH, Moftah MZ, et al. Distribution of nitric oxide-producing cells along spinal cord in urodeles. Front Cell Neurosci. 2014;8:299doi: 10.3389/fncel.2014.00299.
Mahmoud, M. A., Fahmy, G. H., Moftah, M. Z., & Sabry, I. (2014). Distribution of nitric oxide-producing cells along spinal cord in urodeles. Frontiers in cellular neuroscience, 8299. https://doi.org/10.3389/fncel.2014.00299
Mahmoud, Mayada A, et al. "Distribution of nitric oxide-producing cells along spinal cord in urodeles." Frontiers in cellular neuroscience vol. 8 (2014): 299. doi: https://doi.org/10.3389/fncel.2014.00299
Mahmoud MA, Fahmy GH, Moftah MZ, Sabry I. Distribution of nitric oxide-producing cells along spinal cord in urodeles. Front Cell Neurosci. 2014 Sep 25;8:299. doi: 10.3389/fncel.2014.00299. eCollection 2014. PMID: 25309330; PMCID: PMC4174862.
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Front Cell Neurosci. 2014 Sep 25;8:299. doi: 10.3389/fncel.2014.00299. eCollection 2014.

Distribution of nitric oxide-producing cells along spinal cord in urodeles.

Frontiers in cellular neuroscience

Mayada A Mahmoud, Gehan H Fahmy, Marie Z Moftah, Ismail Sabry

Affiliations

  1. Faculty of Medicine, Institut de Neurosciences des Systèmes, Unités Mixtes de Recherche Institut National de la Santé et de la Recherche Médicale 1106, Aix-Marseille University Marseille, France.
  2. Zoology Department, Faculty of Science, Alexandria University Alexandria, Egypt.

PMID: 25309330 PMCID: PMC4174862 DOI: 10.3389/fncel.2014.00299

Abstract

Nitric oxide is a unique neurotransmitter, which participates in many physiological and pathological processes in the organism. There are little data about the neuronal nitric oxide synthase immunoreactivity in the spinal cord of amphibians. In this respect, the present study aims to investigate the distribution of nitric oxide producing cells in the spinal cord of urodele and to find out the possibility of a functional locomotory role to this neurotransmitter. The results of the present study demonstrate a specific pattern of NADPH-d labeling in the selected amphibian model throughout the spinal cord length as NADPH-d-producing cells and fibers were present in almost all segments of the spinal cord of the salamander investigated. However, their number, cytological characteristics and labeling intensity varied significantly. It was noticed that the NO-producing cells (NO-PC) were accumulated in the ventral side of certain segments in the spinal cord corresponding to the brachial and sacral plexuses. In addition, the number of NO-PC was found to be increased also at the beginning of the tail and this could be due to the fact that salamanders are tetrapods having bimodal locomotion, namely swimming and walking.

Keywords: NADPH-d labeling; neurotransmitter agents; nitric oxide; spinal cord; urodeles

References

  1. Proc Natl Acad Sci U S A. 1991 Apr 1;88(7):2811-4 - PubMed
  2. Brain Behav Evol. 2002;60(2):80-100 - PubMed
  3. Brain Res Bull. 2000 Nov 15;53(5):595-603 - PubMed
  4. J Comp Neurol. 1996 Feb 19;365(4):511-25 - PubMed
  5. Ned Tijdschr Geneeskd. 2001 Mar 10;145(10):466-74 - PubMed
  6. J Comp Neurol. 1997 Jan 6;377(1):121-41 - PubMed
  7. Brain Res. 1994 May 23;646(2):279-91 - PubMed
  8. Cell Tissue Res. 1999 Oct;298(1):45-54 - PubMed
  9. J Chem Neuroanat. 2008 Jan;35(1):12-32 - PubMed
  10. Physiol Res. 2000;49(1):151-5 - PubMed
  11. Ann N Y Acad Sci. 2005 Dec;1057:64-84 - PubMed
  12. Neuroscience. 1993 Jun;54(4):845-57 - PubMed
  13. Cell Tissue Res. 1994 Nov;278(2):299-309 - PubMed
  14. Neuroscientist. 2005 Aug;11(4):294-307 - PubMed
  15. Life Sci. 2011 Apr 25;88(17-18):746-52 - PubMed
  16. J Comp Neurol. 1993 Aug 8;334(2):192-208 - PubMed
  17. Annu Rev Neurosci. 1994;17:153-83 - PubMed
  18. Neuron. 1991 Oct;7(4):615-24 - PubMed
  19. J Neurobiol. 1999 Jan;38(1):1-15 - PubMed
  20. J Urol. 1995 Jan;153(1):212-7 - PubMed
  21. J Morphol. 1992 Apr;212(1):87-97 - PubMed
  22. Neurosci Lett. 1995 Jan 30;184(3):204-7 - PubMed
  23. J Anat. 2002 Mar;200(Pt 3):297-308 - PubMed
  24. Neurosci Res. 2004 Sep;50(1):55-66 - PubMed
  25. Eur J Neurosci. 2006 Oct;24(7):1907-22 - PubMed
  26. Neurosci Lett. 1992 Dec 7;147(2):217-20 - PubMed
  27. Brain Behav Evol. 1999 Sep;54(3):147-58 - PubMed
  28. Brain Res Dev Brain Res. 1995 May 26;86(1-2):155-66 - PubMed
  29. J Comp Neurol. 2002 Mar 25;445(1):59-77 - PubMed
  30. Prog Neurobiol. 1994 Jan;42(1):129-60 - PubMed
  31. Acta Anat (Basel). 1994;150(1):16-24 - PubMed
  32. Neuroscience. 2003;116(1):167-78 - PubMed
  33. Nitric Oxide. 1999 Oct;3(5):383-92 - PubMed
  34. Neurosci Lett. 2008 May 9;436(2):265-8 - PubMed
  35. Brain Res. 1996 Jul 15;727(1-2):49-64 - PubMed
  36. Neurosci Res. 2001 Dec;41(4):299-332 - PubMed
  37. Anat Embryol (Berl). 1998 Mar;197(3):229-47 - PubMed
  38. Eur J Neurosci. 2004 Oct;20(8):1995-2007 - PubMed
  39. Acta Neuropathol. 1964 Jan 2;3:238-49 - PubMed
  40. J Comp Neurol. 1999 Apr 5;406(2):263-84 - PubMed
  41. Prog Brain Res. 2007;161:171-83 - PubMed
  42. Anat Embryol (Berl). 1999 Feb;199(2):185-98 - PubMed
  43. Neuroscience. 1994 Apr;59(3):561-78 - PubMed
  44. Trends Neurosci. 2001 Feb;24(2):99-106 - PubMed
  45. J Neurosci. 1995 May;15(5 Pt 2):4033-45 - PubMed
  46. Neuroscience. 1992;46(4):755-84 - PubMed
  47. J Mol Histol. 2005 Jun;36(5):325-9 - PubMed
  48. J Chem Neuroanat. 1996 Jun;10(3-4):273-8 - PubMed
  49. Neuroreport. 1998 Oct 5;9(14):3141-6 - PubMed
  50. Anat Rec (Hoboken). 2013 Oct;296(10):1603-14 - PubMed
  51. Ann N Y Acad Sci. 2005 Aug;1053:422-34 - PubMed
  52. News Physiol Sci. 1999 Feb;14:30-36 - PubMed
  53. Clin Sci (Lond). 1999 Jul;97(1):5-17 - PubMed
  54. J Comp Neurol. 1996 Mar 25;367(1):54-69 - PubMed
  55. J Chem Neuroanat. 2002 Feb;23(2):105-21 - PubMed
  56. Neuroscience. 1998 Aug;85(3):847-62 - PubMed
  57. J Comp Neurol. 1995 Feb 13;352(3):398-420 - PubMed

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