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Madabhavi I, Patel A, Revannasiddaiah S, et al. Primary esophageal Burkitt's lymphoma: a rare case report and review of literature. Gastroenterol Hepatol Bed Bench. 2014;7(4):230-7
Madabhavi, I., Patel, A., Revannasiddaiah, S., Choudhary, M., Anand, A., Das, P., Panchal, H., Parikh, S., Aagre, S., Bhardava, V., & Talele, A. (2014). Primary esophageal Burkitt's lymphoma: a rare case report and review of literature. Gastroenterology and hepatology from bed to bench, 7(4), 230-7.
Madabhavi, Irappa, et al. "Primary esophageal Burkitt's lymphoma: a rare case report and review of literature." Gastroenterology and hepatology from bed to bench vol. 7,4 (2014): 230-7.
Madabhavi I, Patel A, Revannasiddaiah S, Choudhary M, Anand A, Das P, Panchal H, Parikh S, Aagre S, Bhardava V, Talele A. Primary esophageal Burkitt's lymphoma: a rare case report and review of literature. Gastroenterol Hepatol Bed Bench. 2014;7(4):230-7. PMID: 25289138; PMCID: PMC4185878.
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Gastroenterol Hepatol Bed Bench. 2014;7(4):230-7.

Primary esophageal Burkitt's lymphoma: a rare case report and review of literature.

Gastroenterology and hepatology from bed to bench

Irappa Madabhavi, Apurva Patel, Swaroop Revannasiddaiah, Mukesh Choudhary, Asha Anand, Priyanka Das, Harsha Panchal, Sonia Parikh, Suhas Aagre, Vishalkumar Bhardava, Avinash Talele

Affiliations

  1. Department of Medical and Pediatric Oncology, GCRI, Ahmedabad, Gujarat, India.
  2. Department of Radiation Oncology, Swami Rama Cancer, Hospital & Research Institute, Government Medical College- Haldwani, Nainithal, Uttarakhand, India.
  3. Department of Radiology, GCRI, Ahmedabad, Gujarat, India.

PMID: 25289138 PMCID: PMC4185878

Abstract

Esophageal lymphoma is a rare condition, accounting for less than 1% of all gastrointestinal lymphomas. Primary extra nodal esophageal lymphoma constitutes less than 0.2% cases of the total esophageal lymphomas. The definition of primary GI lymphoma has differed among authors. The etiology of the disease is unknown, with the role of Epstein-Barr virus being controversial. The common symptoms of patients with esophageal lymphoma include dysphasia, odynophagia, weight loss, chest pain or present as a result of complications. Burkitt's lymphoma is one of the fastest growing human malignancies, with a 100% replication rate. Endemic, sporadic (non-endemic) and immunodeficient variants have been recognized. The diagnosis of Burkitt's lymphoma relies on morphologic findings, immunophenotyping results, and cytogenetic features. Burkitt's lymphoma is usually treated with LMB-96 protocol depending on the risk stratification. We present a case of primary esophageal Burkitt's lymphoma, which has been successfully treated with LMB-96 protocol. An extensive review of literature did not reveal a single case of esophageal Burkitt's lymphoma. To the best of our knowledge this is the first case report in the world literature with diagnosis of primary esophageal Burkitt's lymphoma.

Keywords: Burkitt’s lymphoma (BL); COPADM; Diffuse large B-cell lymphoma (DLBCL); Gastrointestinal (GI) lymphoma; Non-Hodgkin’s Lymphoma (NHL)

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