Adv Biomed Res. 2014 Sep 12;3:191. doi: 10.4103/2277-9175.140623. eCollection 2014.
Advanced biomedical research
Maseumeh Dashti, Ahmad Chitsaz
PMID: 25317409 PMCID: PMC4190451 DOI: 10.4103/2277-9175.140623
Hallervorden-Spatz disease (HSD) is a rare disorder characterized by progressive extrapyramidal dysfunction and dementia. Hallervorden and Spatz first described the disease, in 1922 as a form of familial brain degeneration characterized by iron deposition in the brain. Here we present four HSD cases with different clinical pictures.
Keywords: Extra pyramdal sign; Hallervorden-Spatz Disease; dementia; dystonia