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J Clin Biochem Nutr. 2014 Sep;55(2):135-42. doi: 10.3164/jcbn.14-30. Epub 2014 Jul 31.

Coffee consumption is inversely associated with depressive status in Japanese patients with type 2 diabetes.

Journal of clinical biochemistry and nutrition

Katsuhisa Omagari, Mika Sakaki, Yuki Tsujimoto, Yukiko Shiogama, Akiko Iwanaga, Makiko Ishimoto, Asami Yamaguchi, Miki Masuzumi, Miku Kawase, Mayuko Ichimura, Takatoshi Yoshitake, Yoshiyuki Miyahara

Affiliations

  1. Department of Nutrition, Faculty of Nursing and Nutrition, University of Nagasaki, 1-1-1 Manabino, Nagayo-cho, Nagasaki 851-2195, Japan.
  2. Dietary Cure Unit, Nagasaki Memorial Hospital, 1-11-54 Fukahori, Nagasaki 851-0301, Japan.
  3. Division of Nutritional Sciences, Graduate School of Human Health Science, University of Nagasaki, 1-1-1 Manabino, Nagayo-cho, Nagasaki 851-2195, Japan.
  4. Department of Internal Medicine, Nagasaki Memorial Hospital, 1-11-54 Fukahori, Nagasaki 851-0301, Japan.

PMID: 25320461 PMCID: PMC4164615 DOI: 10.3164/jcbn.14-30

Abstract

Depression has been reported to be more prevalent among diabetic patients than non-diabetic individuals. Although depression and diabetes are causally and bi-directionally related, the influence of food intake frequency on depressive symptoms in diabetic patients has not been fully evaluated. This cross-sectional study analyzed data obtained from 89 patients with type 2 diabetes who completed self-administered questionnaires regarding food intake frequency, diabetic variables, physical activity and depressive states. The prevalence of a "definite" depressive state was 16.9%. The duration of diabetes, hemoglobin A1c levels, diabetic microvascular complications and physical activity levels were similar between depressed and non-depressed patients. Daily intakes of total lipids, n-6 polyunsaturated fatty acids and lipid energy ratios were significantly lower, and the carbohydrate energy ratio was significantly higher in depressed than in non-depressed patients. Coffee consumption was inversely associated with depressive symptoms, but no significant association was found between tea or green tea consumption and depressive symptoms. The logistic regression analysis showed that coffee consumption was an independent predictor of non-depressed status in diabetic patients. This might be due to biologically active compounds containing in coffee other than caffeine.

Keywords: coffee consumption; depression; diabetes mellitus; food intake

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