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Dunlop BW, Kaye JL, Youngner C, et al. Assessing Treatment-Resistant Posttraumatic Stress Disorder: The Emory Treatment Resistance Interview for PTSD (E-TRIP). Behav Sci (Basel). 2014;4(4):511-527doi: 10.3390/bs4040511.
Dunlop, B. W., Kaye, J. L., Youngner, C., & Rothbaum, B. (2014). Assessing Treatment-Resistant Posttraumatic Stress Disorder: The Emory Treatment Resistance Interview for PTSD (E-TRIP). Behavioral sciences (Basel, Switzerland), 4(4), 511-527. https://doi.org/10.3390/bs4040511
Dunlop, Boadie W, et al. "Assessing Treatment-Resistant Posttraumatic Stress Disorder: The Emory Treatment Resistance Interview for PTSD (E-TRIP)." Behavioral sciences (Basel, Switzerland) vol. 4,4 (2014): 511-527. doi: https://doi.org/10.3390/bs4040511
Dunlop BW, Kaye JL, Youngner C, Rothbaum B. Assessing Treatment-Resistant Posttraumatic Stress Disorder: The Emory Treatment Resistance Interview for PTSD (E-TRIP). Behav Sci (Basel). 2014 Dec 08;4(4):511-527. doi: 10.3390/bs4040511. PMID: 25494488; PMCID: PMC4287702.
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Behav Sci (Basel). 2014 Dec 08;4(4):511-527. doi: 10.3390/bs4040511.

Assessing Treatment-Resistant Posttraumatic Stress Disorder: The Emory Treatment Resistance Interview for PTSD (E-TRIP).

Behavioral sciences (Basel, Switzerland)

Boadie W Dunlop, Joanna L Kaye, Cole Youngner, Barbara Rothbaum

Affiliations

  1. Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 12 Executive Park Drive, 3rd Floor, Atlanta, GA 30329, USA. [email protected].
  2. Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 12 Executive Park Drive, 3rd Floor, Atlanta, GA 30329, USA. [email protected].
  3. Rollins School of Public Health, Emory University, 1518 Clifton Road, Atlanta, GA 30322, USA. [email protected].
  4. Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 12 Executive Park Drive, 3rd Floor, Atlanta, GA 30329, USA. [email protected].

PMID: 25494488 PMCID: PMC4287702 DOI: 10.3390/bs4040511

Abstract

Patients with posttraumatic stress disorder (PTSD) who fail to respond to established treatments are at risk for chronic disability and distress. Although treatment-resistant PTSD (TR-PTSD) is a common clinical problem, there is currently no standard method for evaluating previous treatment outcomes. Development of a tool that could quantify the degree of resistance to previously provided treatments would inform research in patients with PTSD. We conducted a systematic review of PTSD treatment trials to identify medication and psychotherapy interventions proven to be efficacious for PTSD. We then developed a semi-structured clinician interview called the Emory Treatment Resistance Interview for PTSD (E-TRIP). The E-TRIP includes clinician-administered questions to assess the adequacy and benefit derived from past treatment trials. For each adequately delivered treatment to which the patient failed to respond, a score is assigned depending on the strength of evidence supporting the treatment's efficacy. The E-TRIP provides a comprehensive assessment of prior PTSD treatments that should prove valuable for researchers studying TR-PTSD and evaluating the efficacy of new treatments for patients with PTSD. The E-TRIP is not intended to guide treatment; rather, the tool quantifies the level of treatment resistance in patients with PTSD in order to standardize TR-PTSD in the research domain.

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