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J Plant Biol. 2014 Apr;57(2):67-79. doi: 10.1007/s12374-014-0902-7.

Master Regulators in Plant Glucose Signaling Networks.

Journal of plant biology = Singmul Hakhoe chi

Jen Sheen

Affiliations

  1. Department of Molecular Biology and Centre for Computational and Integrative Biology, Massachusetts General Hospital, and Department of Genetics, Harvard Medical School, Boston, MA 02114, USA.

PMID: 25530701 PMCID: PMC4270195 DOI: 10.1007/s12374-014-0902-7

Abstract

The daily life of photosynthetic plants revolves around sugar production, transport, storage and utilization, and the complex sugar metabolic and signaling networks integrate internal regulators and environmental cues to govern and sustain plant growth and survival. Although diverse sugar signals have emerged as pivotal regulators from embryogenesis to senescence, glucose is the most ancient and conserved regulatory signal that controls gene and protein expression, cell-cycle progression, central and secondary metabolism, as well as growth and developmental programs. Glucose signals are perceived and transduced by two principal mechanisms: direct sensing through glucose sensors and indirect sensing via a variety of energy and metabolite sensors. This review focuses on the comparative and functional analyses of three glucose-modulated master regulators in

Keywords: energy sensor kinase; glucose signaling networks; hexokinase; target of rapamycin kinase

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