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Indian J Hematol Blood Transfus. 2014 Sep;30:394-7. doi: 10.1007/s12288-014-0431-z. Epub 2014 Jul 16.

Diagnostic and therapeutic quandaries in a patient with primary hepatic lymphoma and concurrent hepatitis C infection.

Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion

Muhajir Mohamed, Ruchira Fernando

Affiliations

  1. Haematology Department, Launceston General Hospital, Launceston, TAS Australia ; Launceston Clinical School, University of Tasmania, Launceston, TAS Australia.
  2. Pathology Department, Launceston General Hospital, Launceston, TAS Australia.

PMID: 25332629 PMCID: PMC4192212 DOI: 10.1007/s12288-014-0431-z

Abstract

Primary hepatic lymphoma (PHL) is a very rare sub-type of non-Hodgkin's lymphoma and hepatitis C infection may be a contributory factor. The association of hepatitis C infection and PHL causes difficulties in management since safety of rituximab in such situations is unclear due to lack of evidence. The role of anti-viral therapy in combination with chemotherapy is also uncertain. We describe the diagnostic and therapeutic challenges posed by a patient who was diagnosed with PHL and concurrent hepatitis C infection.

Keywords: Hepatitis C; Primary hepatic lymphoma

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