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Steinberg J, Katz T, Mousli A, et al. Corneal biomechanical changes after crosslinking for progressive keratoconus with the corneal visualization scheimpflug technology. J Ophthalmol. 2014;2014:579190doi: 10.1155/2014/579190.
Steinberg, J., Katz, T., Mousli, A., Frings, A., Casagrande, M. K., Druchkiv, V., Richard, G., & Linke, S. J. (2014). Corneal biomechanical changes after crosslinking for progressive keratoconus with the corneal visualization scheimpflug technology. Journal of ophthalmology, 2014579190. https://doi.org/10.1155/2014/579190
Steinberg, Johannes, et al. "Corneal biomechanical changes after crosslinking for progressive keratoconus with the corneal visualization scheimpflug technology." Journal of ophthalmology vol. 2014 (2014): 579190. doi: https://doi.org/10.1155/2014/579190
Steinberg J, Katz T, Mousli A, Frings A, Casagrande MK, Druchkiv V, Richard G, Linke SJ. Corneal biomechanical changes after crosslinking for progressive keratoconus with the corneal visualization scheimpflug technology. J Ophthalmol. 2014;2014:579190. doi: 10.1155/2014/579190. Epub 2014 Sep 22. PMID: 25332832; PMCID: PMC4190167.
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J Ophthalmol. 2014;2014:579190. doi: 10.1155/2014/579190. Epub 2014 Sep 22.

Corneal biomechanical changes after crosslinking for progressive keratoconus with the corneal visualization scheimpflug technology.

Journal of ophthalmology

Johannes Steinberg, Toam Katz, Aiham Mousli, Andreas Frings, Maria K Casagrande, Vasyl Druchkiv, Gisbert Richard, Stephan J Linke

Affiliations

  1. Department of Ophthalmology, UKE-University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany ; Care-Vision Germany, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany.
  2. Department of Ophthalmology, UKE-University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany.

PMID: 25332832 PMCID: PMC4190167 DOI: 10.1155/2014/579190

Abstract

Purpose. To evaluate the effect of corneal crosslinking in progressive keratoconus by applying in vivo corneal visualization Scheimpflug technology. Design. Longitudinal retrospective study. Subjects and Controls. Seventeen eyes of patients treated with corneal crosslinking for progressive keratoconus. Methods. Corneal visualization Scheimpflug technology analyses (research software version 6.07r08) of subjects with progressive keratoconus before and 3 months after corneal crosslinking (CXL) were reviewed retrospectively. t-test (for normal distribution) and Wilcoxon matched-pairs test (if not normally distributed) were used to test for statistically significant differences between pre- and post-CXL analyses. Results. We demonstrated statistically significant differences for the intraocular pressure (median: +3 mmHg, P = 0.004), the central corneal pachymetry (pachy; mean: -35 µm, P < 0.001), the timespan between the air impulse release and the first applanation of the cornea (A1time; median: +0.12 ms, P < 0.05), and the timespan between the air impulse release and the second applanation of the cornea (A2time; median: -37 ms, P < 0.05). Conclusions. With the A1time and the A2time, we identified two parameters that demonstrated a statistically significant improvement of the biomechanical properties of the cornea after CXL. Despite the known initial decrease of the pachymetry after CXL, none of the analyzed parameters indicated a progression of the keratoconus.

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