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Casale R, Romanenko Y, Allegri M. 5% lidocaine medicated plaster double effect in a case of orofacial localized neuropathic pain. J Pain Res. 2014;7:639-43doi: 10.2147/JPR.S70317.
Casale, R., Romanenko, Y., & Allegri, M. (2014). 5% lidocaine medicated plaster double effect in a case of orofacial localized neuropathic pain. Journal of pain research, 7639-43. https://doi.org/10.2147/JPR.S70317
Casale, Roberto, et al. "5% lidocaine medicated plaster double effect in a case of orofacial localized neuropathic pain." Journal of pain research vol. 7 (2014): 639-43. doi: https://doi.org/10.2147/JPR.S70317
Casale R, Romanenko Y, Allegri M. 5% lidocaine medicated plaster double effect in a case of orofacial localized neuropathic pain. J Pain Res. 2014 Nov 24;7:639-43. doi: 10.2147/JPR.S70317. eCollection 2014. PMID: 25473307; PMCID: PMC4247146.
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J Pain Res. 2014 Nov 24;7:639-43. doi: 10.2147/JPR.S70317. eCollection 2014.

5% lidocaine medicated plaster double effect in a case of orofacial localized neuropathic pain.

Journal of pain research

Roberto Casale, Yuriy Romanenko, Massimo Allegri

Affiliations

  1. Department of Clinical Neurophysiology and Pain Rehabilitation Unit, Foundation "Salvatore Maugeri", Research and Care Institute, IRCCS, Pavia, Italy ; EFIC Montescano Pain School, Montescano, Italy.
  2. EFIC Montescano Pain School, Montescano, Italy ; Department of Neurology, Lugansk City Hospital 4, Lugansk, Ukraine.
  3. Department of Surgical Science, University of Parma, Parma, Italy ; Pain Therapy Service, Azienda Ospedaliera Universitaria Parma, University of Parma, Parma, Italy ; Study In Multidisciplinary Pain Research Group, Pavia, Italy.

PMID: 25473307 PMCID: PMC4247146 DOI: 10.2147/JPR.S70317

Abstract

Localized neuropathic pain (LNP) is a type of neuropathic pain that is characterized by "consistent and limited area(s) of maximum pain associated with negative or positive sensory signs and/or spontaneous symptoms characteristic of neuropathic pain". This definition encompasses a huge number of neuropathic orofacial pain syndromes. We present a case report of a patient who was affected with sleep apnea syndrome treated with nocturnal oxygen mask delivery, in whom orofacial LNP hampered the wearing of a mask due to unbearable burning and throbbing pain. The application of 5% lidocaine medicated plaster during the night led to an impressive reduction of both the pain level and the size of the painful area due to the plaster's pharmacological mechanisms, which were associated with a secondary benefit due to its mechanical protective action. This case report shows how these two factors could be of clinical value and have to be considered more systematically in the treatment of LNP in reducing pain and the size of the painful area.

Keywords: 5% lidocaine medicated plaster; localized neuropathic pain; topical treatment; trigeminal pain

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