Display options
Cite
Bonello M, Larner AJ, Marson AG. Profound amnesia after temporal lobectomy: an autoimmune process resembling patient h.m.?. Case Rep Neurol. 2014;6(3):251-5doi: 10.1159/000369058.
Bonello, M., Larner, A. J., & Marson, A. G. (2014). Profound amnesia after temporal lobectomy: an autoimmune process resembling patient h.m.?. Case reports in neurology, 6(3), 251-5. https://doi.org/10.1159/000369058
Bonello, Michael, et al. "Profound amnesia after temporal lobectomy: an autoimmune process resembling patient h.m.?." Case reports in neurology vol. 6,3 (2014): 251-5. doi: https://doi.org/10.1159/000369058
Bonello M, Larner AJ, Marson AG. Profound amnesia after temporal lobectomy: an autoimmune process resembling patient h.m.?. Case Rep Neurol. 2014 Oct 31;6(3):251-5. doi: 10.1159/000369058. eCollection 2014 Sep. PMID: 25473398; PMCID: PMC4249997.
Copy Download .nbib Format: NLM
Share it on

Case Rep Neurol. 2014 Oct 31;6(3):251-5. doi: 10.1159/000369058. eCollection 2014 Sep.

Profound amnesia after temporal lobectomy: an autoimmune process resembling patient h.m.?.

Case reports in neurology

Michael Bonello, Andrew J Larner, Anthony G Marson

Affiliations

  1. Walton Centre for Neurology and Neurosurgery, Liverpool, UK.

PMID: 25473398 PMCID: PMC4249997 DOI: 10.1159/000369058

Abstract

We describe a patient who developed significant cognitive decline with profound amnesia following non-dominant temporal lobectomy for refractory seizures, in whom the original suspicion of structural pathology was revised following the discovery of clinical and neuropathological markers of inflammation, neuropsychological evidence of bilateral involvement, and high titres of antibodies directed against glutamic acid decarboxylase (GAD). This case adds to the evidence that the diagnosis of non-paraneoplastic anti-GAD limbic encephalitis merits consideration in any patient with a refractory seizure disorder and cognitive decline.

Keywords: Amnesia; Epilepsy; Glutamic acid decarboxylase; Limbic encephalitis; Temporal lobectomy

References

  1. Epilepsia. 2010 May;51(5):760-7 - PubMed
  2. J Neurol Neurosurg Psychiatry. 2010 Oct;81(10 ):1167-9 - PubMed
  3. Ann Neurol. 2010 Apr;67(4):470-8 - PubMed
  4. J Neurol Neurosurg Psychiatry. 1957 Feb;20(1):11-21 - PubMed
  5. J Neurol. 2008 Oct;255(10):1603-4 - PubMed
  6. Brain. 2003 Dec;126(Pt 12):2573-85 - PubMed
  7. J Clin Exp Neuropsychol. 1998 Jun;20(3):310-9 - PubMed
  8. J Am Geriatr Soc. 2005 Apr;53(4):695-9 - PubMed
  9. Eur J Neurol. 2013 Sep;20(9):1297-304 - PubMed
  10. J Psychiatr Res. 1975 Nov;12(3):189-98 - PubMed
  11. Nat Commun. 2014;5:3122 - PubMed
  12. Int J Geriatr Psychiatry. 2006 Nov;21(11):1078-85 - PubMed
  13. Eur J Neurol. 2012 Jun;19(6):827-33 - PubMed
  14. Brain. 2008 Oct;131(Pt 10):2553-63 - PubMed

Publication Types