Display options
Share it on

Multidiscip Respir Med. 2014 Sep 03;9(1):46. doi: 10.1186/2049-6958-9-46. eCollection 2014.

The AIMAR recommendations for early diagnosis of chronic obstructive respiratory disease based on the WHO/GARD model*.

Multidisciplinary respiratory medicine

Stefano Nardini, Isabella Annesi-Maesano, Mario Del Donno, Maurizio Delucchi, Germano Bettoncelli, Vincenzo Lamberti, Carlo Patera, Mario Polverino, Antonio Russo, Carlo Santoriello, Patrizio Soverina

Affiliations

  1. Pulmonary and TB Unit, Vittorio Veneto General Hospital, Vittorio Veneto, TV, Italy.
  2. EPAR, INSERM UMRS-1136 IPLESP, Paris, France ; EPAR, Paris Université Pierre et Marie Curie, UMRS-1136 IPLESP, Paris, France.
  3. Respiratory Unit, "G. Rummo" Hospital, Benevento, Italy.
  4. Internal Medicine Unit , Saluzzo Hospital, ASL CN1 Regione Piemonte, Saluzzo, CN, Italy.
  5. General Practitioner, Brescia, SIMG Area Respiratoria, Florence, Italy.
  6. Sport Medicine, ULSS 7 Regione Veneto, Vittorio Veneto TV, Italy.
  7. General Practitioner, Regione Veneto, San Donà di Piave, VE, Italy.
  8. Provincial Respiratory Pole, ASL Salerno, Salerno, Italy.
  9. Respiratory Function Unit, Polla Hospital, ASL Salerno Salerno, Italy.
  10. General Practitioner, Naples, SIMG Area Respiratoria, Naples, Italy.

PMID: 25473523 PMCID: PMC4252853 DOI: 10.1186/2049-6958-9-46

Abstract

Respiratory diseases in Italy already now represent an emergency (they are the 3(rd) ranking cause of death in the world, and the 2(nd) if Lung cancer is included). In countries similar to our own, they result as the principal cause for a visit to the general practitioner (GP) and the second main cause after injury for recourse to Emergency Care. Their frequency is probably higher than estimated (given that respiratory diseases are currently underdiagnosed). The trend is towards a further increase due to epidemiologic and demographic factors (foremost amongst which are the widespread diffusion of cigarette smoking, the increasing mean age of the general population, immigration, and pollution). Within the more general problem of chronic disease care, chronic respiratory diseases (CRDs) constitute one of the four national priorities in that they represent an important burden for society in terms of mortality, invalidity, and direct healthcare costs. The strategy suggested by the World Health Organization (WHO) is an integrated approach consisting of three goals: inform about health, reduce risk exposure, improve patient care. The three goals are translated into practice in the three areas of prevention (1-primary, 2-secondary, 3-tertiary) as: 1) actions of primary (universal) prevention targeted at the general population with the aim to control the causes of disease, and actions of Predictive Medicine - again addressing the general population but aimed at measuring the individual's risk for disease insurgence; 2) actions of early diagnosis targeted at groups or - more precisely - subgroups identified as at risk; 3) continuous improvement and integration of care and rehabilitation support - destined at the greatest possible number of patients, at all stages of disease severity. In Italy, COPD care is generally still inadequate. Existing guidelines, institutional and non-institutional, are inadequately implemented: the international guidelines are not always adaptable to the Italian context; the document of the Agency for Regional Healthcare Services (AGE.NA.S) is a more suited compendium for consultation, and the recent joint statement on integrated COPD management of the three major Italian scientific Associations in the respiratory area together with the contribution of a Society of General Medicine deals prevalently with some critical issues (appropriateness of diagnosis, pharmacological treatment, rehabilitation, continuing care); also the document "Care Continuity: Chronic Obstructive Pulmonary Disease (COPD)" of the Global Alliance against chronic Respiratory Diseases (GARD)-Italy does not treat in depth the issue of early diagnosis. The present document - produced by the AIMAR (Interdisciplinary Association for Research in Lung Disease) Task Force for early diagnosis of chronic respiratory disease based on the WHO/GARD model and on available evidence and expertise -after a general examination of the main epidemiologic aspects, proposes to integrate the above-mentioned existing documents. In particular: a) it formally indicates on the basis of the available evidence the modalities and the instruments necessary for carrying out secondary prevention at the primary care level (a pro-active,'case-finding'approach; assessment of the individual's level of risk of COPD; use of short questionnaires for an initial screening based on symptoms; use of simple spirometry for the second level of screening); b) it identifies possible ways of including these activities within primary care practice; c) it places early diagnosis within the "systemic", consequential management of chronic respiratory diseases, which will be briefly described with the aid of schemes taken from the Italian and international reference documents.

Keywords: COPD; Early diagnosis; Guidelines; Prevention; Respiratory diseases

References

  1. Chest. 2003 Jun;123(6):1916-23 - PubMed
  2. Am J Respir Crit Care Med. 2011 Apr 1;183(7):891-7 - PubMed
  3. Eur Respir J. 2002 Oct;20(4):793-4 - PubMed
  4. Arch Bronconeumol. 2010 Dec;46 Suppl 10:14-8 - PubMed
  5. Am J Infect Control. 2011 Feb;39(1):50-5 - PubMed
  6. Clin Respir J. 2012 Apr;6(2):120-7 - PubMed
  7. Chest. 2006 Jun;129(6):1531-9 - PubMed
  8. J Am Geriatr Soc. 2000 May;48(5 Suppl):S146-53 - PubMed
  9. COPD. 2008 Apr;5(2):85-95 - PubMed
  10. Br J Gen Pract. 2004 Mar;54(500):201-6 - PubMed
  11. Eur Respir J. 2007 Feb;29(2):390-417 - PubMed
  12. Chest. 2007 May;131(5 Suppl):4S-42S - PubMed
  13. Prim Care Respir J. 2013 Sep;22(3):331-7 - PubMed
  14. BMJ. 2005 Apr 30;330(7498):1007-11 - PubMed
  15. Int J Chron Obstruct Pulmon Dis. 2012;7:457-94 - PubMed
  16. Thorax. 2008 May;63(5):387-8 - PubMed
  17. Arch Intern Med. 2007 Mar 26;167(6):551-61 - PubMed
  18. J Am Pharm Assoc (2003). 2013 May-Jun;53(3):307-15 - PubMed
  19. Respir Med. 2011 Jun;105(6):907-15 - PubMed
  20. Monaldi Arch Chest Dis. 1999 Apr;54(2):186-8 - PubMed
  21. BMJ. 2002 Jun 8;324(7350):1370 - PubMed
  22. Cochrane Database Syst Rev. 2010 May 12;(5):CD005074 - PubMed
  23. Respir Med. 2006 Feb;100(2):264-72 - PubMed
  24. Monaldi Arch Chest Dis. 2009 Dec;71(4):153-60 - PubMed
  25. Can Respir J. 2009 Sep-Oct;16(5):e51-3 - PubMed
  26. Chest. 2003 May;123(5):1684-92 - PubMed
  27. Prim Care Respir J. 2008 Dec;17(4):238-42 - PubMed
  28. J Exp Med. 2004 Sep 6;200(5):689-95 - PubMed
  29. Int J Chron Obstruct Pulmon Dis. 2009;4:61-77 - PubMed
  30. Chest. 2007 May;131(5):1494-9 - PubMed
  31. Chest. 2012 Aug;142(2):358-66 - PubMed
  32. Chest. 2000 Feb;117(2 Suppl):29S-32S - PubMed
  33. BMJ. 2009 Apr 02;338:b1024 - PubMed
  34. Respirology. 2005 Jun;10(3):323-33 - PubMed
  35. J Manag Care Pharm. 2006 Jul-Aug;12(6):457-65 - PubMed
  36. Chest. 2005 May;127(5):1560-4 - PubMed
  37. Cochrane Database Syst Rev. 2011 Oct 05;(10):CD005305 - PubMed
  38. Respiration. 2005 Sep-Oct;72(5):471-9 - PubMed
  39. Respir Med. 2006 Nov;100(11):1973-80 - PubMed
  40. Regul Toxicol Pharmacol. 2013 Dec;67(3):372-81 - PubMed
  41. Eur Respir J. 2005 Nov;26(5):948-68 - PubMed
  42. Respir Care. 2012 Jun;57(6):1021-7 - PubMed
  43. Eur Respir J. 2005 Aug;26(2):319-38 - PubMed
  44. Thorax. 2006 Dec;61(12):1043-7 - PubMed
  45. BMJ. 2006 Jul 22;333(7560):188-90 - PubMed
  46. Eur Respir J. 2009 May;33(5):1031-8 - PubMed
  47. Chest. 2006 Apr;129(4):844-52 - PubMed
  48. J Assoc Physicians India. 2011 Jun;59:360-4 - PubMed
  49. Respir Care Clin N Am. 1998 Sep;4(3):345-58, vii - PubMed
  50. Ont Health Technol Assess Ser. 2012;12(10):1-65 - PubMed
  51. Int J Chron Obstruct Pulmon Dis. 2012;7:495-502 - PubMed
  52. Respir Care. 2003 Aug;48(8):773-6 - PubMed
  53. Monaldi Arch Chest Dis. 2013 Mar;79(1):6-7 - PubMed
  54. Chest. 2000 May;117(5 Suppl 2):339S-45S - PubMed
  55. Respir Care. 2012 Jan;57(1):136-45; discussion 143-5 - PubMed
  56. Am J Respir Crit Care Med. 2005 Jun 15;171(12):1443-64 - PubMed
  57. Clin Physiol. 1993 Jan;13(1):89-98 - PubMed
  58. Thorax. 1996 Oct;51(10):973-6 - PubMed
  59. Am J Respir Crit Care Med. 2008 Apr 15;177(8):912-27 - PubMed
  60. Eur Respir J. 2003 Aug;22(2):268-73 - PubMed
  61. Scand J Prim Health Care. 2006 Sep;24(3):133-9 - PubMed
  62. Respir Med. 2003 Mar;97 Suppl C:S33-42 - PubMed
  63. Cochrane Database Syst Rev. 2011 Jul 06;(7):CD007718 - PubMed
  64. Addiction. 2005 Aug;100(8):1074-89 - PubMed
  65. Chest. 2008 Jan;133(1):313-4; author reply 314 - PubMed
  66. Am J Respir Crit Care Med. 2006 Jun 15;173(12):1390-413 - PubMed
  67. BMC Fam Pract. 2012 May 28;13:41 - PubMed
  68. Am J Respir Crit Care Med. 2007 Sep 15;176(6):532-55 - PubMed
  69. Respiration. 2012;83(4):344-52 - PubMed
  70. Cochrane Database Syst Rev. 2007 Oct 17;(4):CD002990 - PubMed
  71. Eur Respir J Suppl. 2003 Jun;41:1s-3s - PubMed
  72. COPD. 2005 Jun;2(2):225-32 - PubMed
  73. Int J Chron Obstruct Pulmon Dis. 2010 Nov 24;5:401-6 - PubMed
  74. Int J Chron Obstruct Pulmon Dis. 2009;4:245-51 - PubMed
  75. Respir Med. 2005 Oct;99(10):1311-8 - PubMed
  76. Chest. 2002 May;121(5):1434-40 - PubMed
  77. N Engl J Med. 2004 Mar 4;350(10):1005-12 - PubMed
  78. Eur Respir Rev. 2012 Dec 1;21(126):347-54 - PubMed
  79. Chest. 2006 Apr;129(4):879-85 - PubMed
  80. Am J Respir Crit Care Med. 2010 Oct 1;182(7):890-6 - PubMed
  81. Epidemiol Prev. 2014 Jan-Feb;38(1):38-45 - PubMed
  82. BMC Public Health. 2013 Jan 09;13:15 - PubMed
  83. Am J Clin Nutr. 2012 Jun;95(6):1385-95 - PubMed
  84. Pediatr Allergy Immunol. 2005 May;16(3):254-7 - PubMed
  85. Cochrane Database Syst Rev. 2012 Nov 14;11:CD008033 - PubMed
  86. Eur Respir Rev. 2013 Mar 1;22(127):37-43 - PubMed
  87. Eur Respir J. 2006 Sep;28(3):523-32 - PubMed
  88. Lancet. 1997 May 10;349(9062):1347-52 - PubMed

Publication Types