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Knarborg M, Bendstrup E, Hilberg O. Increasing awareness of corticosteroid hypersensitivity reactions is important. Respirol Case Rep. 2013;1(2):43-5doi: 10.1002/rcr2.13.
Knarborg, M., Bendstrup, E., & Hilberg, O. (2013). Increasing awareness of corticosteroid hypersensitivity reactions is important. Respirology case reports, 1(2), 43-5. https://doi.org/10.1002/rcr2.13
Knarborg, Malene, et al. "Increasing awareness of corticosteroid hypersensitivity reactions is important." Respirology case reports vol. 1,2 (2013): 43-5. doi: https://doi.org/10.1002/rcr2.13
Knarborg M, Bendstrup E, Hilberg O. Increasing awareness of corticosteroid hypersensitivity reactions is important. Respirol Case Rep. 2013 Dec;1(2):43-5. doi: 10.1002/rcr2.13. PMID: 25473540; PMCID: PMC4184525.
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Respirol Case Rep. 2013 Dec;1(2):43-5. doi: 10.1002/rcr2.13.

Increasing awareness of corticosteroid hypersensitivity reactions is important.

Respirology case reports

Malene Knarborg, Elisabeth Bendstrup, Ole Hilberg

Affiliations

  1. Department of Respiratory Diseases, Aarhus University Hospital Aarhus, Denmark.

PMID: 25473540 PMCID: PMC4184525 DOI: 10.1002/rcr2.13

Abstract

Corticosteroid hypersensitivity is a rare, but troublesome condition often mimicking the symptoms of the underlying disease and therefore probably underdiagnosed. Our objective is to underline the importance of increased awareness of corticosteroid hypersensitivity and of determining the tolerability to other corticosteroid preparations and thus identify a safe treatment alternative. We report a case of corticosteroid hypersensitivity in a 65-year-old woman with a history of difficult-to-treat asthma and systemic corticosteroid allergy admitted with increasing dyspnea and dry cough. The patient was diagnosed with hypereosinophilia, apical fibrosis, and basal pulmonary infiltrations. A prick test and a prolonged challenge test were performed to find a suitable corticosteroid to treat her hypereosinophilia. In conclusion, it is compulsory to perform cutaneous prick and intradermal test, but many cases will only be diagnosed correctly by intravenous or oral challenge test.

Keywords: Allergy; corticosteroid; hypersensitivity; steroids

References

  1. J Investig Allergol Clin Immunol. 2006;16(1):51-6 - PubMed
  2. Curr Opin Allergy Clin Immunol. 2010 Aug;10(4):273-9 - PubMed
  3. Ann Allergy Asthma Immunol. 2002 Nov;89(5):439-45; quiz 445-6, 502 - PubMed
  4. Allergy. 2010 Nov;65(11):1376-80 - PubMed
  5. Clin Rev Allergy Immunol. 2014 Aug;47(1):26-37 - PubMed

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