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Respirol Case Rep. 2014 Mar;2(1):45-7. doi: 10.1002/rcr2.44. Epub 2014 Jan 21.

Primary nonseminomatous germ cell tumor in the posterior mediastinum.

Respirology case reports

Yousuke Wada, Toshiki Yokoyama, Hiroshi Yamamoto, Masayuki Hanaoka, Satoshi Kawakami, Tomonobu Koizumi

Affiliations

  1. First Department of Internal Medicine, Shinshu University School of Medicine Asahi Matsumoto, Japan.
  2. Department of Radiology, Shinshu University School of Medicine Asahi Matsumoto, Japan.
  3. Department of Comprehensive Cancer Therapy, Shinshu University School of Medicine Asahi Matsumoto, Japan.

PMID: 25473562 PMCID: PMC4184732 DOI: 10.1002/rcr2.44

Abstract

A 54-year-old man was admitted to our hospital for further examination following a chest radiographic screening test. He was asymptomatic but had an elevated serum concentration of alpha-fetoprotein. Chest computed tomography (CT) and magnetic resonance imaging showed a posterior mediastinal mass in the left thoracic paravertebral region. CT-guided percutaneous needle biopsy was performed, and the histological findings confirmed nonseminomatous germ cell tumor (NSGCT). Gonadal examination and F-18 fluorodeoxyglucose positron emission tomography findings indicated the posterior mediastinum as the origin of the disease. Reports of primary NSGCT in the posterior mediastinum are extremely rare.

Keywords: Alpha-fetoprotein; germ cell tumor; mediastinal tumor; neurogenic tumor

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