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Morita S, Shirai T, Asada K, et al. Pulmonary cryptococcosis presenting with a large cavity. Respirol Case Rep. 2014;2(2):61-3doi: 10.1002/rcr2.49.
Morita, S., Shirai, T., Asada, K., Fujii, M., Suzuki, M., & Suda, T. (2014). Pulmonary cryptococcosis presenting with a large cavity. Respirology case reports, 2(2), 61-3. https://doi.org/10.1002/rcr2.49
Morita, Satoru, et al. "Pulmonary cryptococcosis presenting with a large cavity." Respirology case reports vol. 2,2 (2014): 61-3. doi: https://doi.org/10.1002/rcr2.49
Morita S, Shirai T, Asada K, Fujii M, Suzuki M, Suda T. Pulmonary cryptococcosis presenting with a large cavity. Respirol Case Rep. 2014 Jun;2(2):61-3. doi: 10.1002/rcr2.49. Epub 2014 Feb 25. PMID: 25473568; PMCID: PMC4184507.
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Respirol Case Rep. 2014 Jun;2(2):61-3. doi: 10.1002/rcr2.49. Epub 2014 Feb 25.

Pulmonary cryptococcosis presenting with a large cavity.

Respirology case reports

Satoru Morita, Toshihiro Shirai, Kazuhiro Asada, Masato Fujii, Makoto Suzuki, Takafumi Suda

Affiliations

  1. Department of Respiratory Medicine, Shizuoka General Hospital Shizuoka, Japan.
  2. Department of Pathology, Shizuoka General Hospital Shizuoka, Japan.
  3. Second Department of Internal Medicine, Hamamatsu University School of Medicine Hamamatsu, Japan.

PMID: 25473568 PMCID: PMC4184507 DOI: 10.1002/rcr2.49

Abstract

A 78-year-old woman who was receiving corticosteroids for rheumatoid arthritis was admitted to our hospital to have her fever, hemoptysis, diarrhea, and chest x-ray abnormalities, which were unresponsive to antibiotics, investigated. A chest computed tomography scan revealed infiltrative shadows and a large cavity in the right lower lobe. Laboratory tests revealed a white blood cell count of 13,100/μL, a serum C-reactive protein level of 8.75 mg/dL, a serum albumin level of 1.4 g/dL, and positivity for Cryptococcus antigen. Grocott staining of a transbronchial lung biopsy specimen detected black-brown fungi. Also, a stool sample was positive for C lostridium difficile toxin, leading to a diagnosis of pulmonary cryptococcosis and pseudomembranous colitis. The patient was given 200 mg/day intravenous fosfluconazole and 1500 mg/day oral metronidazole, and her condition improved. Immunocompromised hosts with pulmonary cryptococcosis demonstrate a wide variety of radiographic abnormalities, including nodules, cavitation, and infiltration.

Keywords: Cavitation; Cryptococcus; immunocompromised host

References

  1. Chest. 2006 Feb;129(2):333-40 - PubMed
  2. Eur Respir J. 2012 Nov;40(5):1191-200 - PubMed
  3. AJR Am J Roentgenol. 1984 May;142(5):893-6 - PubMed

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