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Shrikhande SV, Sirohi B, Barreto SG, et al. Indian Council of Medical Research consensus document for the management of gastric cancer. Indian J Med Paediatr Oncol. 2014;35(4):239-43doi: 10.4103/0971-5851.144970.
Shrikhande, S. V., Sirohi, B., Barreto, S. G., Chacko, R. T., Parikh, P. M., Pautu, J., Arya, S., Patil, P., Chilukuri, S. C., Ganesh, B., Kaur, T., Shukla, D., & Rath, G. S. (2014). Indian Council of Medical Research consensus document for the management of gastric cancer. Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology, 35(4), 239-43. https://doi.org/10.4103/0971-5851.144970
Shrikhande, Shailesh V, et al. "Indian Council of Medical Research consensus document for the management of gastric cancer." Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology vol. 35,4 (2014): 239-43. doi: https://doi.org/10.4103/0971-5851.144970
Shrikhande SV, Sirohi B, Barreto SG, Chacko RT, Parikh PM, Pautu J, Arya S, Patil P, Chilukuri SC, Ganesh B, Kaur T, Shukla D, Rath GS. Indian Council of Medical Research consensus document for the management of gastric cancer. Indian J Med Paediatr Oncol. 2014 Oct;35(4):239-43. doi: 10.4103/0971-5851.144970. PMID: 25538398; PMCID: PMC4264267.
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Indian J Med Paediatr Oncol. 2014 Oct;35(4):239-43. doi: 10.4103/0971-5851.144970.

Indian Council of Medical Research consensus document for the management of gastric cancer.

Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology

Shailesh V Shrikhande, Bhawna Sirohi, Savio G Barreto, Raju T Chacko, Purvish M Parikh, Jeremy Pautu, Supreeta Arya, Prachi Patil, Srinivas C Chilukuri, B Ganesh, Tanvir Kaur, Deepak Shukla, Goura Shankar Rath

Affiliations

  1. Department of Surgical Oncology, Kiran Mazumdar Shaw Cancer Centre, Narayana Health, Bangalore, India.
  2. Department of Medical Oncology, Kiran Mazumdar Shaw Cancer Centre, Narayana Health, Bangalore, India.
  3. Institute of Digestive and Hepatobiliary Sciences, Medanta - The Medicity, Gurgaon, Haryana, India.
  4. Department of Medical Oncology, Christian Medical College, Vellore, Tamil Nadu, India.
  5. Department of Medical Oncology, Mizoram Sate Cancer Institute, Aizwal, Mizoram, India.
  6. Department of Radiodiagnosis, Tata Memorial Centre, Mumbai, Maharashtra, India.
  7. Department of DDCN, Tata Memorial Centre, Mumbai, Maharashtra, India.
  8. Department of Radiotherapy, Yashoda Hospital, Hyderabad, Andhra Pradesh, India.
  9. Department of Epidemiology, Tata Memorial Centre, Mumbai, Maharashtra, India.
  10. Indian Council of Medical Research, All India Institute of Medical Sciences, New Delhi, India.
  11. Department of Radiotherapy, All India Institute of Medical Sciences, New Delhi, India.

PMID: 25538398 PMCID: PMC4264267 DOI: 10.4103/0971-5851.144970

Abstract

The document is based on consensus among the experts and best available evidence pertaining to Indian population and is meant for practice in India.Evaluation of a patient with newly diagnosed gastric cancer should include essential tests: A standard white light endoscopy with multiple biopsies from the tumor for confirmation of the diagnosis, a computed tomography (CT) scan (multi-detector or helical) of the abdomen and pelvis for staging with a CT chest or chest X-ray, and complete blood counts, renal and liver function tests. Endoscopic ultrasonography/ magnetic resonance imaging/positron emission tomography-CT is not recommended for all patients.For early stage disease (IA/B, N0), surgery alone is recommended. The need for adjuvant treatment would be guided by the histopathological analysis of the resected specimen.For locally advanced stage (IB, N(+) to IIIC), neoadjuvant chemotherapy may be considered to downstage the disease followed by surgery. This may be followed by adjuvant chemotherapy (as part of the peri-operative chemotherapy regimen)Patients with stage IV/metastatic disease must be assessed for chemotherapy versus best supportive care on an individual basis.Clinical examination including history and physical examination are recommended at each follow-up visit, with a yearly CT scan of the chest, abdomen, and pelvis.HER2 testing should be considered in patients with metastatic disease.5-FU may be replaced with capecitabine if patients do not have gastric outlet obstruction. Cisplatin may be replaced with oxaliplatin in the regimens.

Keywords: Diagnosis; Indian Council of Medical Research; gastric cancer; guidelines; treatment

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