Display options
Cite
Manthena S, Ramesh A, Srikanth A, et al. Comparative evaluation of subgingivally delivered chlorhexidine varnish and chlorhexidine gel in reducing microbial count after mechanical periodontal therapy. J Basic Clin Pharm. 2014;6(1):24-8doi: 10.4103/0976-0105.145775.
Manthena, S., Ramesh, A., Srikanth, A., Ramoji Rao, M. V., Preethi, P. L., & Samatha, Y. P. (2014). Comparative evaluation of subgingivally delivered chlorhexidine varnish and chlorhexidine gel in reducing microbial count after mechanical periodontal therapy. Journal of basic and clinical pharmacy, 6(1), 24-8. https://doi.org/10.4103/0976-0105.145775
Manthena, Sathish, et al. "Comparative evaluation of subgingivally delivered chlorhexidine varnish and chlorhexidine gel in reducing microbial count after mechanical periodontal therapy." Journal of basic and clinical pharmacy vol. 6,1 (2014): 24-8. doi: https://doi.org/10.4103/0976-0105.145775
Manthena S, Ramesh A, Srikanth A, Ramoji Rao MV, Preethi PL, Samatha YP. Comparative evaluation of subgingivally delivered chlorhexidine varnish and chlorhexidine gel in reducing microbial count after mechanical periodontal therapy. J Basic Clin Pharm. 2014 Dec;6(1):24-8. doi: 10.4103/0976-0105.145775. PMID: 25538468; PMCID: PMC4268626.
Copy Download .nbib Format: NLM
Share it on

J Basic Clin Pharm. 2014 Dec;6(1):24-8. doi: 10.4103/0976-0105.145775.

Comparative evaluation of subgingivally delivered chlorhexidine varnish and chlorhexidine gel in reducing microbial count after mechanical periodontal therapy.

Journal of basic and clinical pharmacy

Sathish Manthena, Amitha Ramesh, Adusumilli Srikanth, M V Ramoji Rao, P Lakshmi Preethi, Y Pallavi Samatha

Affiliations

  1. Department of Periodontics, Drs. Sudha and Nageswara Rao Siddhartha Institute of Dental Sciences, Chinnoutpalli, India.
  2. Department of Periodontics, A. B. Shetty Memorial Institute of Dental Sciences, Deralakatte, Mangaluru, Karnataka, India.

PMID: 25538468 PMCID: PMC4268626 DOI: 10.4103/0976-0105.145775

Abstract

CONTEXT: Antimicrobial efficacy of subgingival chlorhexidine (CHX) application using two different vehicles of delivery.

AIMS: The aim was to evaluate the efficacy of CHX varnish and gel as an adjunct to scaling and root planing (SRP) in reducing microbial count within moderate to deep periodontal pockets.

SETTINGS AND DESIGN: Experimental parallel mouth study.

SUBJECTS AND METHODS: A total of 30 subjects between the age groups 25 and 55 years having moderate to severe periodontitis, with pocket depth ≥ 5 mm were selected for the study. The selected patients were randomized into three groups of 10 each. Subjects in Group 1 received SRP followed by subgingival application of CHX varnish, subjects in Group 2 received SRP followed by subgingival application of CHX gel, subjects in Group 3 received SRP alone. Subgingival plaque samples were collected to estimate mean motile and nonmotile microbial counts using dark field microscopy at baseline, 1 week, 1 month, and 3 months.

RESULTS: After 3 months, there was statistically significant reduction in nonmotile microbial count in all the three groups. Motile microbial count was significantly reduced in all the three groups till 1 month from baseline. Only subjects in Group 1 who received subgingival CHXvarnish after SRP showed a significant reduction in motile microbial count till 3 months from baseline.

CONCLUSIONS: Subgingival application of highly concentrated CHX varnish following SRP is beneficial in reducing microbial count in moderate to deep periodontal pockets.

Keywords: Chlorhexidine; gel; periodontitis; scaling and root planing; varnish

References

  1. J Clin Periodontol. 1981 Feb;8(1):57-72 - PubMed
  2. J Clin Periodontol. 1992 Apr;19(4):240-4 - PubMed
  3. Swed Dent J. 1992;16(5):183-9 - PubMed
  4. J Dent Res. 1989 Dec;68(12):1786-9 - PubMed
  5. Ann Periodontol. 1996 Nov;1(1):821-78 - PubMed
  6. J Periodontal Res. 1970;5(2):79-83 - PubMed
  7. J Clin Periodontol. 1999 Jun;26(6):341-6 - PubMed
  8. J Periodontol. 2006 Mar;77(3):437-43 - PubMed
  9. J Clin Periodontol. 1991 Apr;18(4):245-51 - PubMed
  10. Spec Care Dentist. 1994 Jul-Aug;14(4):158-63 - PubMed
  11. J Biol Buccale. 1991 Dec;19(4):343-8 - PubMed

Publication Types