Display options
Cite
Saunders EF, Novick DM, Fernandez-Mendoza J, et al. Sleep quality during euthymia in bipolar disorder: the role of clinical features, personality traits, and stressful life events. Int J Bipolar Disord. 2013;1:16doi: 10.1186/2194-7511-1-16.
Saunders, E. F., Novick, D. M., Fernandez-Mendoza, J., Kamali, M., Ryan, K. A., Langenecker, S. A., Gelenberg, A. J., & McInnis, M. G. (2013). Sleep quality during euthymia in bipolar disorder: the role of clinical features, personality traits, and stressful life events. International journal of bipolar disorders, 116. https://doi.org/10.1186/2194-7511-1-16
Saunders, Erika Fh, et al. "Sleep quality during euthymia in bipolar disorder: the role of clinical features, personality traits, and stressful life events." International journal of bipolar disorders vol. 1 (2013): 16. doi: https://doi.org/10.1186/2194-7511-1-16
Saunders EF, Novick DM, Fernandez-Mendoza J, Kamali M, Ryan KA, Langenecker SA, Gelenberg AJ, McInnis MG. Sleep quality during euthymia in bipolar disorder: the role of clinical features, personality traits, and stressful life events. Int J Bipolar Disord. 2013 Sep 13;1:16. doi: 10.1186/2194-7511-1-16. eCollection 2013. PMID: 25505683; PMCID: PMC4230686.
Copy Download .nbib Format: NLM
Share it on

Int J Bipolar Disord. 2013 Sep 13;1:16. doi: 10.1186/2194-7511-1-16. eCollection 2013.

Sleep quality during euthymia in bipolar disorder: the role of clinical features, personality traits, and stressful life events.

International journal of bipolar disorders

Erika Fh Saunders, Danielle M Novick, Julio Fernandez-Mendoza, Masoud Kamali, Kelly A Ryan, Scott A Langenecker, Alan J Gelenberg, Melvin G McInnis

Affiliations

  1. University of Illinois at Chicago, Chicago, IL 60612 USA ; University of Illinois at Chicago, Chicago, IL 60612 USA ; University of Illinois at Chicago, Chicago, IL 60612 USA.
  2. University of Illinois at Chicago, Chicago, IL 60612 USA ; University of Illinois at Chicago, Chicago, IL 60612 USA.
  3. University of Illinois at Chicago, Chicago, IL 60612 USA.

PMID: 25505683 PMCID: PMC4230686 DOI: 10.1186/2194-7511-1-16

Abstract

BACKGROUND: Poor sleep quality is known to precede the onset of mood episodes and to be associated with poor treatment outcomes in bipolar disorder (BD). We sought to identify modifiable factors that correlate with poor sleep quality in BD independent of residual mood symptoms.

METHODS: A retrospective analysis was conducted to assess the association between the Pittsburgh Sleep Quality Index and clinical variables of interest in euthymic patients with DSM-IV BD (n = 119) and healthy controls (HC; n = 136) participating in the Prechter Longitudinal Study of Bipolar Disorder. Multivariable linear regression models were constructed to investigate the relationship between sleep quality and demographic and clinical variables in BD and HC participants. A unified model determined independent predictors of sleep quality.

RESULTS AND DISCUSSION: Euthymic participants with BD and HC differed in all domains. The best fitting unified multivariable model of poor sleep quality in euthymic participants with BD included rapid cycling (β = .20, p = .03), neuroticism (β = .28, p = 2 × 10(-3)), and stressful life events (β = .20, p = .02). Poor sleep quality often persists during euthymia and can be a target for treatment. Clinicians should remain vigilant for treating subjective sleep complaints independent of residual mood symptoms in those sensitive to poor sleep quality, including individuals with high neuroticism, rapid cycling, and recent stressful life events. Modifiable factors associated with sleep quality should be targeted directly with psychosocial or somatic treatment. Sleep quality may be a useful outcome measure in BD treatment studies.

Keywords: Bipolar disorder; Neuroticism; Rapid cycling; Sleep; Stress

References

  1. Mol Psychiatry. 1998 Jul;3(4):342-5 - PubMed
  2. Psychol Med. 2011 Aug;41(8):1593-604 - PubMed
  3. Am J Med Genet B Neuropsychiatr Genet. 2007 Jul 5;144B(5):631-5 - PubMed
  4. J Biol Rhythms. 2003 Feb;18(1):80-90 - PubMed
  5. Brain Res. 1991 Aug 23;557(1-2):48-56 - PubMed
  6. Dialogues Clin Neurosci. 2007;9(3):333-42 - PubMed
  7. Hypertension. 2012 Oct;60(4):929-35 - PubMed
  8. Sleep. 1991 Dec;14(6):540-5 - PubMed
  9. Am J Psychiatry. 2004 Oct;161(10):1902-8 - PubMed
  10. Am J Med Genet B Neuropsychiatr Genet. 2008 Jan 5;147B(1):18-26 - PubMed
  11. Sleep. 2009 Apr;32(4):491-7 - PubMed
  12. Transl Psychiatry. 2011 Oct 18;1:e50 - PubMed
  13. Am J Psychiatry. 1994 Aug;151(8):1132-6 - PubMed
  14. Psychiatry Clin Neurosci. 2012 Dec;66(7):553-63 - PubMed
  15. Bipolar Disord. 2013 Mar;15(2):115-37 - PubMed
  16. Maturitas. 2006 Mar 20;53(4):396-404 - PubMed
  17. J Affect Disord. 2005 Dec;89(1-3):45-55 - PubMed
  18. Endocrinol Metab Clin North Am. 2002 Mar;31(1):15-36 - PubMed
  19. J Thyroid Res. 2011;2011:306367 - PubMed
  20. Sleep Med. 2012 Apr;13(4):346-53 - PubMed
  21. Bipolar Disord. 2012 Dec;14(8):870-9 - PubMed
  22. Bipolar Disord. 2006 Dec;8(6):648-64 - PubMed
  23. J Affect Disord. 2011 Nov;134(1-3):416-20 - PubMed
  24. J Pers Soc Psychol. 1993 Aug;65(2):350-9 - PubMed
  25. Arch Gen Psychiatry. 2005 Sep;62(9):996-1004 - PubMed
  26. Br J Psychiatry. 1978 Nov;133:429-35 - PubMed
  27. Eur Neuropsychopharmacol. 2011 Sep;21 Suppl 4:S683-93 - PubMed
  28. Fam Process. 1983 Mar;22(1):69-83 - PubMed
  29. Depress Anxiety. 2004;20(2):92-7 - PubMed
  30. Arch Gen Psychiatry. 1982 Aug;39(8):879-83 - PubMed
  31. Br J Addict. 1991 Sep;86(9):1119-27 - PubMed
  32. J Clin Endocrinol Metab. 2004 May;89(5):2119-26 - PubMed
  33. J Affect Disord. 2012 Dec 10;141(2-3):457-63 - PubMed
  34. J Clin Endocrinol Metab. 2007 Nov;92(11):4199-207 - PubMed
  35. Nord J Psychiatry. 2006;60(2):79-88 - PubMed
  36. Menopause. 2013 Apr;20(4):464-9 - PubMed
  37. J Clin Psychiatry. 2012 Dec;73(12):1563-5 - PubMed
  38. Psychiatr Serv. 2013 Jan;64(1):44-50 - PubMed
  39. Am J Psychiatry. 2006 Feb;163(2):217-24 - PubMed
  40. Addiction. 1993 Jun;88(6):791-804 - PubMed
  41. Bipolar Disord. 2012 Sep;14(6):628-40 - PubMed
  42. Arch Gen Psychiatry. 2003 Sep;60(9):921-8 - PubMed
  43. Am J Psychiatry. 2008 Jul;165(7):820-9 - PubMed
  44. Pharmacogenomics. 2007 Sep;8(9):1097-100 - PubMed
  45. Bipolar Disord. 2005 Apr;7(2):176-86 - PubMed
  46. Depress Anxiety. 2012 Aug;29(8):739-46 - PubMed
  47. J Affect Disord. 1995 Apr 4;33(4):233-43 - PubMed
  48. Psychiatry Res. 2012 Dec 30;200(2-3):252-7 - PubMed
  49. Br J Psychiatry. 2006 Jul;189:20-5 - PubMed
  50. Maturitas. 2012 Aug;72(4):359-66 - PubMed
  51. J Affect Disord. 2010 May;122(3):285-93 - PubMed
  52. Aust N Z J Psychiatry. 2005 Apr;39(4):244-8 - PubMed
  53. Psychosom Med. 2010 May;72(4):397-403 - PubMed
  54. Psychosom Med. 1981 Oct;43(5):439-51 - PubMed
  55. Arch Gen Psychiatry. 2007 May;64(5):543-52 - PubMed
  56. Am J Psychiatry. 2003 Sep;160(9):1696-8 - PubMed
  57. Sleep. 2010 Apr;33(4):459-65 - PubMed
  58. Mol Psychiatry. 1998 Jul;3(4):346-9 - PubMed
  59. Arch Gen Psychiatry. 1994 Nov;51(11):849-59; discussion 863-4 - PubMed
  60. Psychol Med. 2012 Jul;42(7):1449-59 - PubMed
  61. Sleep Med. 2009 Sep;10 Suppl 1:S3-6 - PubMed
  62. Am J Psychiatry. 2005 Jan;162(1):50-7 - PubMed
  63. Am J Med Genet B Neuropsychiatr Genet. 2003 Nov 15;123B(1):23-6 - PubMed
  64. Sleep. 2012 May 01;35(5):689-97 - PubMed
  65. J Psychosom Res. 2007 Aug;63(2):157-66 - PubMed
  66. Arch Gen Psychiatry. 2003 Sep;60(9):914-20 - PubMed
  67. Sleep Med Clin. 2007 Jun;2(2):279-291 - PubMed
  68. Psychiatry Res. 1989 May;28(2):193-213 - PubMed
  69. J Behav Ther Exp Psychiatry. 2010 Jun;41(2):145-9 - PubMed
  70. J Abnorm Psychol. 2012 Feb;121(1):39-50 - PubMed
  71. Bipolar Disord. 2007 Aug;9(5):490-5 - PubMed
  72. J Neurol Neurosurg Psychiatry. 1960 Feb;23:56-62 - PubMed
  73. Bipolar Disord. 2011 Aug-Sep;13(5-6):466-73 - PubMed
  74. Can J Psychiatry. 2008 Jun;53(6):361-70 - PubMed
  75. J Clin Psychiatry. 2002 Jun;63(6):528-33 - PubMed
  76. J Psychiatr Res. 2011 Aug;45(8):1027-35 - PubMed
  77. J Pers Soc Psychol. 1988 May;54(5):853-63 - PubMed
  78. Diabetes Care. 2009 Nov;32(11):1980-5 - PubMed
  79. Sleep. 2009 Dec;32(12):1547 - PubMed
  80. Bipolar Disord. 2012 Aug;14(5):527-36 - PubMed

Publication Types

Grant support