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Shukla L, Kandasamy A, Kesavan M, et al. Baclofen in the short-term maintenance treatment of benzodiazepine dependence. J Neurosci Rural Pract. 2014;5:S53-4doi: 10.4103/0976-3147.145203.
Shukla, L., Kandasamy, A., Kesavan, M., & Benegal, V. (2014). Baclofen in the short-term maintenance treatment of benzodiazepine dependence. Journal of neurosciences in rural practice, 5S53-4. https://doi.org/10.4103/0976-3147.145203
Shukla, Lekhansh, et al. "Baclofen in the short-term maintenance treatment of benzodiazepine dependence." Journal of neurosciences in rural practice vol. 5 (2014): S53-4. doi: https://doi.org/10.4103/0976-3147.145203
Shukla L, Kandasamy A, Kesavan M, Benegal V. Baclofen in the short-term maintenance treatment of benzodiazepine dependence. J Neurosci Rural Pract. 2014 Nov;5:S53-4. doi: 10.4103/0976-3147.145203. PMID: 25540541; PMCID: PMC4271384.
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J Neurosci Rural Pract. 2014 Nov;5:S53-4. doi: 10.4103/0976-3147.145203.

Baclofen in the short-term maintenance treatment of benzodiazepine dependence.

Journal of neurosciences in rural practice

Lekhansh Shukla, Arun Kandasamy, Muralidharan Kesavan, Vivek Benegal

Affiliations

  1. Department of Psychiatry, Centre for Addiction Medicine, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India.

PMID: 25540541 PMCID: PMC4271384 DOI: 10.4103/0976-3147.145203

Abstract

Benzodiazepine (BZD) dependence is a significant public health problem. Apart from the long-term tapering doses of BZD, no others drugs are available for the maintenance treatment of BZD dependence. Baclofen has been used in alcohol and other drug dependence as long-term anti-craving agent. Since alcohol and BZD act through the GABA receptor, we attempted to study the effect of Baclofen as maintenance treatment in a series of five cases with BZD dependence.

Keywords: Anti-craving; baclofen; benzodiazepines; dependence; gamma-aminobutyric acid B; maintenance

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