Display options
Cite
Pereira VC, de Freitas CC, Luvizutto GJ, et al. Stroke as the First Clinical Manifestation of Takayasu's Arteritis. Case Rep Neurol. 2014;6(3):271-4doi: 10.1159/000369783.
Pereira, V. C., de Freitas, C. C., Luvizutto, G. J., Sobreira, M. L., Peixoto, D. E., Magalhães, I. d. o. . N., Bazan, R., & Braga, G. P. (2014). Stroke as the First Clinical Manifestation of Takayasu's Arteritis. Case reports in neurology, 6(3), 271-4. https://doi.org/10.1159/000369783
Pereira, Vanessa Caldeira, et al. "Stroke as the First Clinical Manifestation of Takayasu's Arteritis." Case reports in neurology vol. 6,3 (2014): 271-4. doi: https://doi.org/10.1159/000369783
Pereira VC, de Freitas CC, Luvizutto GJ, Sobreira ML, Peixoto DE, Magalhães Ido N, Bazan R, Braga GP. Stroke as the First Clinical Manifestation of Takayasu's Arteritis. Case Rep Neurol. 2014 Nov 26;6(3):271-4. doi: 10.1159/000369783. eCollection 2014 Sep. PMID: 25566058; PMCID: PMC4280462.
Copy Download .nbib Format: NLM
Share it on

Case Rep Neurol. 2014 Nov 26;6(3):271-4. doi: 10.1159/000369783. eCollection 2014 Sep.

Stroke as the First Clinical Manifestation of Takayasu's Arteritis.

Case reports in neurology

Vanessa Caldeira Pereira, Carlos Clayton Macedo de Freitas, Gustavo José Luvizutto, Marcone Lima Sobreira, Daniel Escobar Bueno Peixoto, Inaldo do Nascimento Magalhães, Rodrigo Bazan, Gabriel Pereira Braga

Affiliations

  1. Department of Neurology, University Estadual Paulista Júlio de Mesquita Filho, Botucatu, Brazil.
  2. Department of Interventional Radiology, University Estadual Paulista Júlio de Mesquita Filho, Botucatu, Brazil.
  3. Department of Neurorehabilitation, University Estadual Paulista Júlio de Mesquita Filho, Botucatu, Brazil.
  4. Department of Stroke Unit, Botucatu School of Medicine, University Estadual Paulista Júlio de Mesquita Filho, Botucatu, Brazil.

PMID: 25566058 PMCID: PMC4280462 DOI: 10.1159/000369783

Abstract

Takayasu's arteritis is a chronic inflammatory disease, and neurological symptoms occur in 50% of cases, most commonly including headache, dizziness, visual disturbances, convulsive crisis, transient ischemic attack, stroke and posterior reversible encephalopathy syndrome. The aim of this study was to report the case of a young Brazilian female with a focal neurological deficit. She presented with asymmetry of brachial and radial pulses, aphasia, dysarthria and right hemiplegia. Stroke was investigated extensively in this young patient. Only nonspecific inflammatory markers such as velocity of hemosedimentation and C-reactive protein were elevated. During hospitalization, clinical treatment was performed with pulse therapy showing improvement in neurological recuperation on subsequent days. In the chronic phase, the patient was submitted to medicated angioplasty of the brachiocephalic trunk with paclitaxel, with significant improvement of the stenosis. At the 6-month follow-up, the neurological exam presented mild dysarthria, faciobrachial predominant disproportionate hemiparesis, an NIHSS score of 4 and a modified Rankin Scale score of 3 (moderate incapacity). In conclusion, Takayasu's arteritis must be recognized as a potential cause of ischemic stroke in young females.

Keywords: Ischemic stroke; Takayasu's arteritis; Vasculitis of the central nervous system

References

  1. Rheumatology (Oxford). 2010 Oct;49(10):1806-14 - PubMed
  2. Ann Intern Med. 1994 Jun 1;120(11):919-29 - PubMed
  3. J Clin Pathol. 2002 Jul;55(7):481-6 - PubMed
  4. Acta Neurol Belg. 2007 Mar;107(1):18-21 - PubMed
  5. Clin Exp Rheumatol. 2009 Jan-Feb;27(1 Suppl 52):S59-64 - PubMed

Publication Types