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Albayrak G, Aykut K, Karacelik M, et al. Bedside surgery to treat patent ductus arteriosus in low-birth-weight premature infants. Open J Cardiovasc Surg. 2014;7:1-4doi: 10.4137/OJCS.S16156.
Albayrak, G., Aykut, K., Karacelik, M., Soylar, R., Karaarslan, K., Abud, B., Guzeloglu, M., & Hazan, E. (2014). Bedside surgery to treat patent ductus arteriosus in low-birth-weight premature infants. Open journal of cardiovascular surgery, 71-4. https://doi.org/10.4137/OJCS.S16156
Albayrak, Gökhan, et al. "Bedside surgery to treat patent ductus arteriosus in low-birth-weight premature infants." Open journal of cardiovascular surgery vol. 7 (2014): 1-4. doi: https://doi.org/10.4137/OJCS.S16156
Albayrak G, Aykut K, Karacelik M, Soylar R, Karaarslan K, Abud B, Guzeloglu M, Hazan E. Bedside surgery to treat patent ductus arteriosus in low-birth-weight premature infants. Open J Cardiovasc Surg. 2014 Aug 17;7:1-4. doi: 10.4137/OJCS.S16156. eCollection 2014. PMID: 25512700; PMCID: PMC4251059.
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Open J Cardiovasc Surg. 2014 Aug 17;7:1-4. doi: 10.4137/OJCS.S16156. eCollection 2014.

Bedside surgery to treat patent ductus arteriosus in low-birth-weight premature infants.

Open journal of cardiovascular surgery

Gökhan Albayrak, Koray Aykut, Mustafa Karacelik, Ramazan Soylar, Kemal Karaarslan, Burçin Abud, Mehmet Guzeloglu, Eyup Hazan

Affiliations

  1. Department of Cardiovascular Surgery, Izmir University, Medical Park Hospital, Izmir, Turkey.
  2. Department of Cardiovascular Surgery, Dr. Behcet Uz Children Hospital, Izmir, Turkey.
  3. Department of Pediatry, Izmir University, Medical Park Hospital, Izmir, Turkey.
  4. Department of Cardiovascular Surgery, Tepecik Research Hospital, Izmir, Turkey.

PMID: 25512700 PMCID: PMC4251059 DOI: 10.4137/OJCS.S16156

Abstract

BACKGROUND: Patent ductus arteriosus (PDA) is commonly seen in premature infants with low birth weights (LBW). It is a condition that has high mortality and morbidity rates. Early closure of the ductus arteriosus may require surgery or medical treatment. However, the decision of first medical approach for symptomatic PDA closure is still debated. In this study, we compared the surgical and medical treatments for the closure of PDA in premature LBW infants.

METHODS: This study included 27 premature infants whose birth weights were lower than 1500 g, who were born in the period between 2011 and 2013 and had symptomatic PDA. Patients were separated into two groups: groups A and B. Group A included patients whose PDAs were closed with medical treatment (n = 16), and group B included patients who had undergone surgical operations for PDA closure (n = 11).

RESULTS: There were no statistically significant differences between groups A and B when the groups were compared in terms of birth weight, gestational age, respiratory distress syndrome (RDS), necrotizing enterocolitis (NEC), sepsis, intraventricular hemorrhage (IVH), retinopathy of prematurity (ROP), and pneumothorax. Although the mortality rate was determined to be lower in group B (2 out of 11, 18.1%) than in group A (7 out of 16, 43.7%), no statistically significant difference was found between the two groups. A statistically significant increase was determined in the incidence of kidney function loss in patient group that received Ibuprofen, a medical treatment, in comparison to the patients who had surgery.

CONCLUSION: In conclusion, surgery is a safe method to repair PDA in premature LBW infants. Although there is no remarkable difference between surgery and medical treatment, we suggest that a surgical approach may be used as a first choice to repair PDA considering the lower rate of mortality and morbidity and higher rate of closure compared to medical treatment.

Keywords: low birth weight; patent ductus arteriosus; surgery

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