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Grummett TS, Fitzgibbon SP, Lewis TW, et al. Constitutive spectral EEG peaks in the gamma range: suppressed by sleep, reduced by mental activity and resistant to sensory stimulation. Front Hum Neurosci. 2014;8:927doi: 10.3389/fnhum.2014.00927.
Grummett, T. S., Fitzgibbon, S. P., Lewis, T. W., DeLosAngeles, D., Whitham, E. M., Pope, K. J., & Willoughby, J. O. (2014). Constitutive spectral EEG peaks in the gamma range: suppressed by sleep, reduced by mental activity and resistant to sensory stimulation. Frontiers in human neuroscience, 8927. https://doi.org/10.3389/fnhum.2014.00927
Grummett, Tyler S, et al. "Constitutive spectral EEG peaks in the gamma range: suppressed by sleep, reduced by mental activity and resistant to sensory stimulation." Frontiers in human neuroscience vol. 8 (2014): 927. doi: https://doi.org/10.3389/fnhum.2014.00927
Grummett TS, Fitzgibbon SP, Lewis TW, DeLosAngeles D, Whitham EM, Pope KJ, Willoughby JO. Constitutive spectral EEG peaks in the gamma range: suppressed by sleep, reduced by mental activity and resistant to sensory stimulation. Front Hum Neurosci. 2014 Nov 21;8:927. doi: 10.3389/fnhum.2014.00927. eCollection 2014. PMID: 25484861; PMCID: PMC4240063.
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Front Hum Neurosci. 2014 Nov 21;8:927. doi: 10.3389/fnhum.2014.00927. eCollection 2014.

Constitutive spectral EEG peaks in the gamma range: suppressed by sleep, reduced by mental activity and resistant to sensory stimulation.

Frontiers in human neuroscience

Tyler S Grummett, Sean P Fitzgibbon, Trent W Lewis, Dylan DeLosAngeles, Emma M Whitham, Kenneth J Pope, John O Willoughby

Affiliations

  1. School of Computer Science, Engineering and Mathematics, and Medical Device Research Institute, Flinders University Adelaide, SA, Australia ; School of Medicine, and Centre for Neuroscience, Flinders University Adelaide, SA, Australia.
  2. School of Computer Science, Engineering and Mathematics, and Medical Device Research Institute, Flinders University Adelaide, SA, Australia.
  3. School of Medicine, and Centre for Neuroscience, Flinders University Adelaide, SA, Australia.

PMID: 25484861 PMCID: PMC4240063 DOI: 10.3389/fnhum.2014.00927

Abstract

OBJECTIVE: In a systematic study of gamma activity in neuro-psychiatric disease, we unexpectedly observed distinctive, apparently persistent, electroencephalogram (EEG) spectral peaks in the gamma range (25-100 Hz). Our objective, therefore, was to examine the incidence, distribution and some of the characteristics of these peaks.

METHODS: High sample-rate, 128-channel, EEG was recorded in 603 volunteers (510 with neuropsychiatric disorders, 93 controls), whilst performing cognitive tasks, and converted to power spectra. Peaks of spectral power, including in the gamma range, were determined algorithmically for all electrodes. To determine if peaks were stable, 24-h ambulatory recordings were obtained from 16 subjects with peaks. In 10 subjects, steady-state responses to stimuli at peak frequency were compared with off-peak-frequency stimulation to determine if peaks were a feature of underlying network resonances and peaks were evaluated with easy and hard versions of oddball tasks to determine if peaks might be influenced by mental effort.

RESULTS: 57% of 603 subjects exhibited peaks >2 dB above trough power at or above 25 Hz. Larger peaks (>5 dB) were present in 13% of subjects. Peaks were distributed widely over the scalp, more frequent centrally. Peaks were present through the day and were suppressed by slow-wave-sleep. Steady-state responses were the same with on- or off-peak sensory stimulation. In contrast, mental effort resulted in reductions in power and frequency of gamma peaks, although the suppression did not correlate with level of effort.

CONCLUSIONS: Gamma EEG can be expressed constitutively as concentrations of power in narrow or wide frequency bands that play an, as yet, unknown role in cognitive activity.

SIGNIFICANCE: These findings expand the described range of rhythmic EEG phenomena. In particular, in addition to evoked, induced and sustained gamma band activity, gamma activity can be present constitutively in spectral peaks.

Keywords: EEG bands; electroencephalogram; mental difficulty; neuro-psychiatric disorder; oddball task; steady-state responses

References

  1. J Neural Eng. 2013 Oct;10(5):056014 - PubMed
  2. Clin Neurophysiol. 2007 Aug;118(8):1877-88 - PubMed
  3. J Neurosci. 1996 Oct 15;16(20):6402-13 - PubMed
  4. Clin Neurophysiol. 2008 May;119(5):1166-75 - PubMed
  5. Clin Neurophysiol. 1999 Mar;110(3):524-37 - PubMed
  6. J Neurophysiol. 1989 Sep;62(3):711-22 - PubMed
  7. Clin Neurophysiol. 2004 Aug;115(8):1802-9 - PubMed
  8. Neuroimage. 2012 Jan 2;59(1):673-81 - PubMed
  9. J Neurosci. 2009 Nov 4;29(44):13962-70 - PubMed
  10. Clin Neurophysiol. 2006 Jun;117(6):1228-43 - PubMed
  11. J Neurosci. 1999 Aug 15;19(16):7152-61 - PubMed
  12. Clin Electroencephalogr. 2001 Jul;32(3):139-44 - PubMed
  13. J Neurol Neurosurg Psychiatry. 2003 Jan;74(1):51-5 - PubMed
  14. Front Hum Neurosci. 2013 Mar 04;7:56 - PubMed
  15. Neurosci Biobehav Rev. 2001 Aug;25(6):465-76 - PubMed
  16. Exp Brain Res. 1999 Nov;129(2):247-59 - PubMed
  17. Fiziol Cheloveka. 2010 May-Jun;36(3):138-41 - PubMed
  18. J Neurosci. 2002 Dec 1;22(23 ):10501-6 - PubMed
  19. Exp Brain Res. 2001 Apr;137(3-4):346-53 - PubMed
  20. J Neurosci. 1998 Jun 1;18(11):4244-54 - PubMed
  21. Biol Cybern. 2005 Mar;92(3):177-85 - PubMed
  22. Neuroscience. 1999;94(4):1005-18 - PubMed
  23. Neuroimage. 2006 Feb 15;29(4):1106-16 - PubMed
  24. Conf Proc IEEE Eng Med Biol Soc. 2013;2013:2184-7 - PubMed
  25. Trends Cogn Sci. 2001 Jan 1;5(1):16-25 - PubMed

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