Display options
Cite
Beppu K, Osada T, Sakamoto N, et al. Optimal timing for resuming antithrombotic agents and risk factors for delayed bleeding after endoscopic resection of colorectal tumors. Gastroenterol Res Pract. 2014;2014:825179doi: 10.1155/2014/825179.
Beppu, K., Osada, T., Sakamoto, N., Shibuya, T., Matsumoto, K., Nagahara, A., Terai, T., Ogihara, T., & Watanabe, S. (2014). Optimal timing for resuming antithrombotic agents and risk factors for delayed bleeding after endoscopic resection of colorectal tumors. Gastroenterology research and practice, 2014825179. https://doi.org/10.1155/2014/825179
Beppu, Kazuko, et al. "Optimal timing for resuming antithrombotic agents and risk factors for delayed bleeding after endoscopic resection of colorectal tumors." Gastroenterology research and practice vol. 2014 (2014): 825179. doi: https://doi.org/10.1155/2014/825179
Beppu K, Osada T, Sakamoto N, Shibuya T, Matsumoto K, Nagahara A, Terai T, Ogihara T, Watanabe S. Optimal timing for resuming antithrombotic agents and risk factors for delayed bleeding after endoscopic resection of colorectal tumors. Gastroenterol Res Pract. 2014;2014:825179. doi: 10.1155/2014/825179. Epub 2014 Dec 07. PMID: 25548556; PMCID: PMC4273557.
Copy Download .nbib Format: NLM
Share it on

Gastroenterol Res Pract. 2014;2014:825179. doi: 10.1155/2014/825179. Epub 2014 Dec 07.

Optimal timing for resuming antithrombotic agents and risk factors for delayed bleeding after endoscopic resection of colorectal tumors.

Gastroenterology research and practice

Kazuko Beppu, Taro Osada, Naoto Sakamoto, Tomoyoshi Shibuya, Kenshi Matsumoto, Akihito Nagahara, Takeshi Terai, Tatsuo Ogihara, Sumio Watanabe

Affiliations

  1. Department of Gastroenterology, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.

PMID: 25548556 PMCID: PMC4273557 DOI: 10.1155/2014/825179

Abstract

Aim. To examine optimal timing for resuming antithrombotic agents and risk factors for delayed bleeding after endoscopic resection of colorectal tumors. Method. Of 1,970 polyps larger than 10 mm removed by polypectomy, endoscopic mucosal resection, or endoscopic submucosal dissection, delayed bleeding, which was designated as bleeding that occurred 6 or more hours after endoscopic treatment, occurred in 52 cases (2.6%); 156 nonbleeding cases matched for age and gender were controls in this single-institution retrospective case-control study. We investigated (1) patient-factors: resuming antithrombotic agents within 5 days following endoscopic resection, hypertension, and diabetes mellitus; and (2) tumor-factors: morphology, size, location, and resection technique by conditional logistic regression. Results. By multivariate analysis resumption of anticoagulants within 5 days was a significant risk factor for delayed bleeding (OR 10.2; 95% CI = 2.7-38.3; P = 0.0006). But resuming a thienopyridine within 5 days was not (OR 0.9; 95% CI = 0.1-2.6; P = 0.40). Other patient- and tumor-factors were not significant. Conclusion. Resuming anticoagulants within 5 days after endoscopic treatment was associated with delayed bleeding whereas resuming thienopyridines was not.

References

  1. Gastrointest Endosc. 2000 Jun;51(6):690-6 - PubMed
  2. Gastrointest Endosc. 2004 Jan;59(1):44-8 - PubMed
  3. Am J Gastroenterol. 2004 Sep;99(9):1785-9 - PubMed
  4. Endoscopy. 2005 Nov;37(11):1116-22 - PubMed
  5. Nat Clin Pract Gastroenterol Hepatol. 2006 Jan;3(1):43-52 - PubMed
  6. Gastrointest Endosc. 2006 Jul;64(1):73-8 - PubMed
  7. Gastrointest Endosc. 2006 Oct;64(4):556-62 - PubMed
  8. Endoscopy. 2008 Feb;40(2):115-9 - PubMed
  9. Gastrointest Endosc. 2008 Jun;67(7):1076-81 - PubMed
  10. Gastrointest Endosc. 2009 Dec;70(6):1060-70 - PubMed
  11. Am J Gastroenterol. 2011 Jun;106(6):1119-24 - PubMed
  12. Endoscopy. 2011 Jun;43(6):506-11 - PubMed
  13. Dig Endosc. 2014 Jan;26(1):1-14 - PubMed
  14. Jpn J Surg. 1983 Nov;13(6):557-73 - PubMed
  15. Am J Gastroenterol. 1995 Jan;90(1):146-7 - PubMed
  16. N Engl J Med. 1993 Dec 30;329(27):1977-81 - PubMed
  17. Dis Colon Rectum. 1993 Dec;36(12):1126-31 - PubMed
  18. Gastrointest Endosc Clin N Am. 1996 Apr;6(2):343-77 - PubMed
  19. Dis Colon Rectum. 1996 Jul;39(7):806-10 - PubMed

Publication Types