Caspian J Intern Med. 2014;5(4):202-8.
Does vitamin D status correlate with clinical and biochemical features of polycystic ovarysyndrome in high school girls?.
Caspian journal of internal medicine
Reza Ghadimi, Sedighe Esmaeilzadeh, Marmar Firoozpour, Asal Ahmadi
Affiliations
Affiliations
- Social Determinants of Health Research Center, Babol University of Medical Sciences, Babol, Iran. ; Fatemeh Zahra Infertility and Reproductive Health Research Center, Babol University of Medical Sciences, Babol, Iran.
- Fatemeh Zahra Infertility and Reproductive Health Research Center, Babol University of Medical Sciences, Babol, Iran.
- Babol University of Medical Sciences, Babol, Iran.
PMID: 25489430
PMCID: PMC4247482
Abstract
BACKGROUND: Prevalence of polycystic ovary syndrome (PCOs) is increasing particularly among the female adolescents and young women. It has been hypothesized that disturbance in calcium and vitamin-D metabolism may affect the symptoms of this syndrome. This study was designed to investigate the relationship between vitamin-D and calcium with metabolic parameters and other characteristics of the PCOs.
METHODS: The study included 192 Iranian girls (16-20 years old), of whom 104 had PCOs and 88 were non-PCOs controls. Serum 25(OH) D and calcium level was measured. Anthropometric components, endocrine, metabolic components and insulin resistance were determined in PCOs subjects.
RESULTS: Mean 25 (OH) D was significantly lower in cases (9.7±4.8) than controls (12.3±11.9) but calcium level did not differ between the two groups (9.3±0.3 vs 9.4±0.4). No significant correlations were found between 25(OH) D levels and lipid profile, FBS, fasting insulin endocrine parameters such as testosterone, free testosterone, FSH, LH, and prolactin.
CONCLUSION: Although hypovitamionos D was common is PCOs but did not correlate with clinical features or complications of obesity and insulin resistance PCO like severity of syndrome between vitamin-D deficiency and its severity with some features and complications of PCOs including obesity, insulin resistance.
Keywords: Calcium; Polycystic ovary syndrome; Vitamin-D; Younger girls
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