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Proc (Bayl Univ Med Cent). 2015 Jan;28(1):31-3. doi: 10.1080/08998280.2015.11929178.

Metformin-induced lactic acidosis with emphasis on the anion gap.

Proceedings (Baylor University. Medical Center)

Britton Blough, Amber Moreland, Adan Mora

Affiliations

  1. Department of Internal Medicine, Baylor University Medical Center at Dallas.

PMID: 25552792 PMCID: PMC4264704 DOI: 10.1080/08998280.2015.11929178

Abstract

The presence of an anion gap in a diabetic patient, especially if associated with evidence of compromised renal function, should prompt clinicians to consider metformin as a contributing factor. This consideration is especially important in patients with severe anion gaps associated with lactic acidosis out of proportion to the patient's clinical presentation.

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