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Laskar P, Kuwamura N, Yoshinari N, et al. Crystal structure of (2S,4S)-5,5-dimethyl-2-(pyridin-2-yl)-1,3-thia-zolidine-4-carb-oxy-lic acid. Acta Crystallogr Sect E Struct Rep Online. 2014;70:o1264doi: 10.1107/S1600536814024854.
Laskar, P., Kuwamura, N., Yoshinari, N., & Konno, T. (2014). Crystal structure of (2S,4S)-5,5-dimethyl-2-(pyridin-2-yl)-1,3-thia-zolidine-4-carb-oxy-lic acid. Acta crystallographica. Section E, Structure reports online, 70o1264. https://doi.org/10.1107/S1600536814024854
Laskar, Payel, et al. "Crystal structure of (2S,4S)-5,5-dimethyl-2-(pyridin-2-yl)-1,3-thia-zolidine-4-carb-oxy-lic acid." Acta crystallographica. Section E, Structure reports online vol. 70 (2014): o1264. doi: https://doi.org/10.1107/S1600536814024854
Laskar P, Kuwamura N, Yoshinari N, Konno T. Crystal structure of (2S,4S)-5,5-dimethyl-2-(pyridin-2-yl)-1,3-thia-zolidine-4-carb-oxy-lic acid. Acta Crystallogr Sect E Struct Rep Online. 2014 Nov 15;70:o1264. doi: 10.1107/S1600536814024854. eCollection 2014 Dec 01. PMID: 25553035; PMCID: PMC4257406.
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Acta Crystallogr Sect E Struct Rep Online. 2014 Nov 15;70:o1264. doi: 10.1107/S1600536814024854. eCollection 2014 Dec 01.

Crystal structure of (2S,4S)-5,5-dimethyl-2-(pyridin-2-yl)-1,3-thia-zolidine-4-carb-oxy-lic acid.

Acta crystallographica. Section E, Structure reports online

Payel Laskar, Naoto Kuwamura, Nobuto Yoshinari, Takumi Konno

Affiliations

  1. Department of Chemistry, Graduate School of Science, Osaka University, Toyonaka, Osaka 560-0043, Japan.
  2. Department of Chemistry, Graduate School of Science, Osaka University, Toyonaka, Osaka 560-0043, Japan ; CREST, Japan Science and Technology Agency, Toyonaka, Osaka 560-0043, Japan.

PMID: 25553035 PMCID: PMC4257406 DOI: 10.1107/S1600536814024854

Abstract

In the title compound, C11H14N2O2S, the thia-zolidine ring has an envelope conformation with the C atom bonded to the carb-oxy-lic acid group at the flap. Two C atoms of the thia-zolidine ring adopt S conformations. In the crystal, O-H⋯N hydrogen bonds between the amine and carb-oxy-lic acid groups construct a helical chain structure along the a-axis direction. The chains are further connected via weak C-H⋯π contacts, forming a layer parallel to the ac plane.

Keywords: C—H⋯π contacts; crystal structure; hydrogen bonding; thia­zolidine

References

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