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Korean J Anesthesiol. 2014 Dec;67(6):416-20. doi: 10.4097/kjae.2014.67.6.416. Epub 2014 Dec 29.

Ventricular arrhythmia in patients with prolonged QT interval during liver transplantation: two cases report.

Korean journal of anesthesiology

Min-Soo Kim, Na Young Kim, Ji Eun Park, Soon Ho Nam

Affiliations

  1. Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, Seoul, Korea. ; Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Korea.
  2. Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, Seoul, Korea.

PMID: 25558343 PMCID: PMC4280480 DOI: 10.4097/kjae.2014.67.6.416

Abstract

QT interval prolongation is associated with an increased risk of ventricular arrhythmia in various conditions. Cardiac electrophysiologic abnormalities including QT interval prolongation are well documented in patients with advanced liver cirrhosis. We report two cases of patients with QT interval prolongation on preoperative electrocardiography who exhibited repetitive ventricular arrhythmias with significant hemodynamic deterioration during liver transplantation. For the treatment and prevention of ventricular arrhythmias during the intraoperative period, we performed intravenous administration of lidocaine and isoproterenol, corrected imbalances of electrolytes including potassium and magnesium, and prepared a defibrillator. These cases emphasize that preoperative recognition of QT interval prolongation and adequate management to prevent fatal arrhythmias are important in patients undergoing liver transplantation.

Keywords: Arrhythmia; Intraoperative complications; Liver transplantation

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