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AMIA Jt Summits Transl Sci Proc. 2014 Apr 07;2014:96-101. eCollection 2014.

tranSMART: An Open Source Knowledge Management and High Content Data Analytics Platform.

AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science

Elisabeth Scheufele, Dina Aronzon, Robert Coopersmith, Michael T McDuffie, Manish Kapoor, Christopher A Uhrich, Jean E Avitabile, Jinlei Liu, Dan Housman, Matvey B Palchuk

Affiliations

  1. Recombinant By Deloitte, Newton MA ; Harvard Medical School, Boston, MA.
  2. Recombinant By Deloitte, Newton MA.

PMID: 25717408 PMCID: PMC4333702

Abstract

The tranSMART knowledge management and high-content analysis platform is a flexible software framework featuring novel research capabilities. It enables analysis of integrated data for the purposes of hypothesis generation, hypothesis validation, and cohort discovery in translational research. tranSMART bridges the prolific world of basic science and clinical practice data at the point of care by merging multiple types of data from disparate sources into a common environment. The application supports data harmonization and integration with analytical pipelines. The application code was released into the open source community in January 2012, with 32 instances in operation. tranSMART's extensible data model and corresponding data integration processes, rapid data analysis features, and open source nature make it an indispensable tool in translational or clinical research.

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