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J Surg Case Rep. 2015 Jan 12;2015(1). doi: 10.1093/jscr/rju146.

Long-term survival after extended resection of primary atrial myxosarcoma.

Journal of surgical case reports

Diganta Kakaty, Martin Grapow, Bettina Huber, Didier Lardinois

Affiliations

  1. Division of Thoracic Surgery, University Hospital Basel, Basel, Switzerland [email protected].
  2. Division of Cardiac Surgery, University Hospital Basel, Basel, Switzerland.
  3. Institute of Pathology, University Hospital Basel, Basel, Switzerland.
  4. Division of Thoracic Surgery, University Hospital Basel, Basel, Switzerland.

PMID: 25583907 PMCID: PMC4289858 DOI: 10.1093/jscr/rju146

Abstract

The vast majority of adult primary cardiac tumours (75%) are benign. The differentiation between malignant and benign lesions based on imaging is often difficult. Furthermore, it is challenging to distinguish between a cardiac myxoma and a myxosarcoma histologically. We report the case of a 48-year-old female who underwent resection of myxoma. Fourteen months postoperatively, she developed dyspnoea and evidence of local recurrence was observed. An open biopsy was performed and compared with the initially resected specimen. A primary cardiac myxosarcoma was diagnosed. Extended resection of the tumour including a part of the left atrium and the left lung was performed. Follow-up at 4 years shows no radiological evidence of any further recurrence and the patient is satisfied with a good quality of life. Despite the infrequent nature and particularly in view of the poor prognosis of cardiac myxosarcoma with a median overall survival of ∼12-17 months, we were able to demonstrate in our case that, with an extensive medical and surgical therapy and an interdisciplinary approach, a long-term disease-free survival can be achieved.

Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author 2015.

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