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J Clin Med Res. 2015 Mar;7(3):137-44. doi: 10.14740/jocmr2050w. Epub 2014 Dec 29.

Left ventricular diastolic function in hypertension: methodological considerations and clinical implications.

Journal of clinical medicine research

Pasquale Palmiero, Annapaola Zito, Maria Maiello, Matteo Cameli, Pietro Amedeo Modesti, Maria Lorenza Muiesan, Salvatore Novo, Pier Sergio Saba, Pietro Scicchitano, Roberto Pedrinelli, Marco Matteo Ciccone

Affiliations

  1. ASL Department of Cardiology, Brindisi District, Italy.
  2. Cardiovascular Disease Section, Department of Emergency and Organ Transplantation, University of Bari, Italy.
  3. Department of Cardiovascular Diseases, University of Siena, Italy.
  4. Department of Clinical and Experimental Medicine, University of Florence, Florence, Italy.
  5. Clinica Medica, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
  6. Department of Internal Medicine and Cardiovascular Diseases, Palermo, Italy.
  7. Cardiologia, Azienda Ospedaliero-Universitaria di Sassari, Italy.
  8. Dipartimento di Patologia Chirurgica, Medica, Molecolare e dell'Area Critica, Universita di Pisa, Pisa, Italy.

PMID: 25584097 PMCID: PMC4285058 DOI: 10.14740/jocmr2050w

Abstract

The assessment of left ventricular (LV) diastolic function should be an integral part of a routine examination of hypertensive patient; indeed when LV diastolic function is impaired, it is possible to have heart failure even with preserved LV ejection fraction. Left ventricular diastolic dysfunction (LVDD) occurs frequently and is associated to heart disease. Doppler echocardiography is the best tool for early LVDD diagnosis. Hypertension affects LV relaxation and when left ventricular hypertrophy (LVH) occurs, it decreases compliance too, so it is important to calculate Doppler echocardiography parameters, for diastolic function evaluation, in all hypertensive patients. The purpose of our review was to discuss about the strong relationship between LVDD and hypertension, and their relationship with LV systolic function. Furthermore, we aimed to assess the relationship between the arterial stiffness and LV structure and function in hypertensive patients.

Keywords: Diastolic dysfunction; Diastolic function; Hypertension; Left ventricular

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