Display options
Cite
Eren E, Yılmaz N, Aydin O, et al. Anticipatory role of high density lipoprotein and endothelial dysfunction: an overview. Open Biochem J. 2014;8:100-6doi: 10.2174/1874091X01408010100.
Eren, E., Yılmaz, N., Aydin, O., & Ellidağ, H. Y. (2014). Anticipatory role of high density lipoprotein and endothelial dysfunction: an overview. The open biochemistry journal, 8100-6. https://doi.org/10.2174/1874091X01408010100
Eren, Esin, et al. "Anticipatory role of high density lipoprotein and endothelial dysfunction: an overview." The open biochemistry journal vol. 8 (2014): 100-6. doi: https://doi.org/10.2174/1874091X01408010100
Eren E, Yılmaz N, Aydin O, Ellidağ HY. Anticipatory role of high density lipoprotein and endothelial dysfunction: an overview. Open Biochem J. 2014 Dec 31;8:100-6. doi: 10.2174/1874091X01408010100. eCollection 2014. PMID: 25598849; PMCID: PMC4293742.
Copy Download .nbib Format: NLM
Share it on

Open Biochem J. 2014 Dec 31;8:100-6. doi: 10.2174/1874091X01408010100. eCollection 2014.

Anticipatory role of high density lipoprotein and endothelial dysfunction: an overview.

The open biochemistry journal

Esin Eren, Necat Yılmaz, Ozgur Aydin, Hamit Y Ellidağ

Affiliations

  1. Laboratory of Atatürk Hospital, Antalya/Turkey.
  2. Central Laboratories of Antalya Education and Research Hospital of Ministry of Health, Antalya/Turkey.
  3. Laboratory of Batman Maternity and Children's Hospital, Batman/Turkey.

PMID: 25598849 PMCID: PMC4293742 DOI: 10.2174/1874091X01408010100

Abstract

High Density Lipoprotein (HDL) has been witnessed to possess a range of different functions that contribute to its atheroprotective effects. These functions are: the promotion of macrophage cholesterol efflux, reverse cholesterol transport, anti-inflammatory, anti-thrombotic, anti-apoptotic, pro-fibrinolytic and anti-oxidative functions. Paraoxonase 1 (PON1) is an HDL associated enzyme esterase/homocysteinethiolactonase that contributes to the anti-oxidant and anti-atherosclerotic capabilities of HDL. PON1 is directly involved in the etiopathogenesis of atherosclerosis through the modulation of nitric oxide (NO) bioavailability. The aim of this review is to summarize the role of HDL on endothelial homeostasis, and also to describe the recently characterized molecular pathways involved.

Keywords: Endothelial function; high-density lipoprotein; homocysteine; nitric oxide; oxLDL; oxidative stress; paraoxonase.

References

  1. Am J Physiol Endocrinol Metab. 2010 Dec;299(6):E1061-5 - PubMed
  2. Vasc Health Risk Manag. 2005;1(2):119-29 - PubMed
  3. J Biol Chem. 2008 Sep 5;283(36):25074-81 - PubMed
  4. Circ J. 2012;76(12):2779-84 - PubMed
  5. Curr Opin Nephrol Hypertens. 2013 May;22(3):259-65 - PubMed
  6. Circulation. 2000 May 9;101(18):2144-8 - PubMed
  7. Trends Cardiovasc Med. 2007 Jul;17(5):156-61 - PubMed
  8. Curr Opin Lipidol. 2012 Oct;23(5):439-45 - PubMed
  9. Cell Tissue Res. 2012 Aug;349(2):433-46 - PubMed
  10. Expert Rev Cardiovasc Ther. 2013 Mar;11(3):343-53 - PubMed
  11. Amino Acids. 2012 Oct;43(4):1405-17 - PubMed
  12. Cardiovasc Hematol Disord Drug Targets. 2012 Dec;12(2):98-105 - PubMed
  13. Lipids. 2013 Jun;48(6):569-78 - PubMed
  14. Acta Biochim Biophys Sin (Shanghai). 2013 May;45(5):391-400 - PubMed
  15. Panminerva Med. 2012 Jun;54(2):83-90 - PubMed
  16. J Clin Diagn Res. 2014 Sep;8(9):CE01-4 - PubMed
  17. Circulation. 2013 Feb 26;127(8):891-904 - PubMed
  18. Arterioscler Thromb Vasc Biol. 2003 Oct 1;23(10):1724-31 - PubMed
  19. Cardiovasc Diabetol. 2013 Jan 30;12:27 - PubMed
  20. Arterioscler Thromb Vasc Biol. 2003 Feb 1;23(2):168-75 - PubMed
  21. Lipids Health Dis. 2012 Jul 23;11:92 - PubMed
  22. Open Biochem J. 2012;6:78-93 - PubMed
  23. Am J Physiol Cell Physiol. 2011 Sep;301(3):C739-48 - PubMed
  24. Circ J. 2012;76(11):2497-512 - PubMed
  25. J Lipid Res. 2013 May;54(5):1231-40 - PubMed
  26. Biochim Biophys Acta. 2012 Mar;1821(3):490-501 - PubMed
  27. J Cell Biochem. 2009 Jan 1;106(1):119-26 - PubMed
  28. J Alzheimers Dis. 2012;30(2):225-31 - PubMed
  29. Cardiovasc Drugs Ther. 2011 Oct;25(5):379-91 - PubMed
  30. J Am Coll Cardiol. 2008 Jun 10;51(23):2199-211 - PubMed
  31. Circ Res. 2006 Jun 9;98(11):1352-64 - PubMed
  32. PLoS One. 2014 May 23;9(5):e98368 - PubMed
  33. Microvasc Res. 2012 Nov;84(3):297-305 - PubMed
  34. Circ Res. 2004 Oct 15;95(8):764-72 - PubMed
  35. J Physiol Pharmacol. 2008 Dec;59 Suppl 9:155-67 - PubMed
  36. Trends Endocrinol Metab. 2011 Jan;22(1):9-15 - PubMed
  37. Cholesterol. 2011;2011:687939 - PubMed
  38. Nat Rev Cardiol. 2011 May;8(5):266-77 - PubMed
  39. J Clin Invest. 2011 Jul;121(7):2545-8 - PubMed
  40. Biochem Biophys Res Commun. 2000 Jun 16;272(3):872-6 - PubMed
  41. Arterioscler Thromb Vasc Biol. 2010 Feb;30(2):144-50 - PubMed
  42. Circ Res. 2012 Sep 28;111(8):1079-90 - PubMed
  43. Exp Ther Med. 2013 Jun;5(6):1663-1666 - PubMed
  44. Curr Pharm Des. 2007;13(22):2215-27 - PubMed
  45. Gynecol Endocrinol. 2012 Nov;28(11):874-8 - PubMed
  46. J Lipids. 2012;2012:687273 - PubMed
  47. J Lipid Res. 2013 Oct;54(10):2575-85 - PubMed
  48. Lipids Health Dis. 2006 Jan 23;5:1 - PubMed
  49. Cardiovasc J Afr. 2012 May;23(4):222-31 - PubMed
  50. N Am J Med Sci. 2012 Nov;4(11):523-32 - PubMed
  51. EMBO Mol Med. 2012 Apr;4(4):251-68 - PubMed
  52. Endothelium. 2003;10(1):17-21 - PubMed
  53. Circ Res. 2013 Jan 18;112(2):278-88 - PubMed
  54. Cell Mol Biol (Noisy-le-grand). 2006 Dec 31;52(5):4-10 - PubMed
  55. J Clin Invest. 2011 Jul;121(7):2693-708 - PubMed
  56. Arterioscler Thromb Vasc Biol. 2006 Jul;26(7):1545-50 - PubMed
  57. JACC Cardiovasc Interv. 2011 May;4(5):521-9 - PubMed
  58. J Ethnopharmacol. 2013 Jan 9;145(1):162-7 - PubMed
  59. J Biol Chem. 2012 Dec 28;287(53):44645-53 - PubMed
  60. Arch Med Sci. 2012 Feb 29;8(1):138-53 - PubMed
  61. Clin Chem. 2008 May;54(5):788-800 - PubMed
  62. Mediators Inflamm. 2013;2013:612038 - PubMed
  63. Cell Death Differ. 2004 Jul;11 Suppl 1:S56-64 - PubMed
  64. Immunity. 2013 Apr 18;38(4):754-68 - PubMed
  65. Cholesterol. 2013;2013:792090 - PubMed
  66. Med Princ Pract. 2014;23(1):18-23 - PubMed
  67. J Biomed Sci. 2014 Jun 04;21:55 - PubMed
  68. Open Biochem J. 2014 May 16;8:44-51 - PubMed
  69. Circulation. 2006 Sep 12;114(11):1193-201 - PubMed

Publication Types