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Asker M, Asker S, Kucuk U, et al. Relationship between coronary artery disease and pulmonary arterial pressure in patients with chronic obstructive pulmonary disease. Int J Clin Exp Med. 2014;7(12):5837-41
Asker, M., Asker, S., Kucuk, U., Kucuk, H. O., & Ozbay, B. (2014). Relationship between coronary artery disease and pulmonary arterial pressure in patients with chronic obstructive pulmonary disease. International journal of clinical and experimental medicine, 7(12), 5837-41.
Asker, Muntecep, et al. "Relationship between coronary artery disease and pulmonary arterial pressure in patients with chronic obstructive pulmonary disease." International journal of clinical and experimental medicine vol. 7,12 (2014): 5837-41.
Asker M, Asker S, Kucuk U, Kucuk HO, Ozbay B. Relationship between coronary artery disease and pulmonary arterial pressure in patients with chronic obstructive pulmonary disease. Int J Clin Exp Med. 2014 Dec 15;7(12):5837-41. eCollection 2014. PMID: 25664116; PMCID: PMC4307563.
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Int J Clin Exp Med. 2014 Dec 15;7(12):5837-41. eCollection 2014.

Relationship between coronary artery disease and pulmonary arterial pressure in patients with chronic obstructive pulmonary disease.

International journal of clinical and experimental medicine

Muntecep Asker, Selvi Asker, Ugur Kucuk, Hilal Olgun Kucuk, Bulent Ozbay

Affiliations

  1. Department of Cardiology, Van Training and Research Hospital Van, Turkey.
  2. Department of Chest Disease, Van Training and Research Hospital Van, Turkey.
  3. Department of Cardiology, Van Military Hospital Van, Turkey.
  4. Department of Chest Disease, S?tk? Kocman University, Faculty of Medicine Mugla, Turkey.

PMID: 25664116 PMCID: PMC4307563

Abstract

The aim of the present study was to determine whether there is a relationship between coronary artery disease and pulmonary hypertension and whether pulmonary hypertension is an additional risk factor for the presence and extent of coronary artery disease in patients with chronic obstructive pulmonary disease. Patients diagnosed with chronic obstructive pulmonary disease and pulmonary hypertension, and undergone diagnostic coronary angiography for evaluation of suspected coronary artery disease constituted the study group. Patients were divided into two groups according to the presence or absence of coronary artery disease and compared for age, gender, accompanying chronic disease, and pulmonary function tests. A total of 95 patients were recruited in the study. Comparison of the groups revealed that two groups were significantly different on gender (p=0.029), presence of hypertension (p=0.027), and biomass (p=0.040). Correlation analysis of variables revealed that male gender (rs=0.224, p=0.029), hypertension (rs=0.227, p=0.07) were positively correlated with the presence of coronary artery disease. FEV1/FVC ratio (rs=-0.253, p=0.013) and sPAP (rs=-0.215, p=0.037) were negatively correlated with the presence of coronary artery disease. High prevalence of coronary artery disease in patients with pulmonary hypertension secondary to chronic obstructive pulmonary disease was found. However, no correlation between the presence and severity of coronary artery disease and pulmonary hypertension was detected.

Keywords: Coronary artery disease; chronic obstructive; hypertension; pulmonary; pulmonary disease

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