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Randhir J, Chandrasekaran S, Sathiyasekaran M, et al. Hepatic artery Doppler indices in children with extra hepatic portal vein obstruction. J Clin Exp Hepatol. 2013;3(2):102-5doi: 10.1016/j.jceh.2013.04.002.
Randhir, J., Chandrasekaran, S., Sathiyasekaran, M., & Venkataraman, J. (2013). Hepatic artery Doppler indices in children with extra hepatic portal vein obstruction. Journal of clinical and experimental hepatology, 3(2), 102-5. https://doi.org/10.1016/j.jceh.2013.04.002
Randhir, Jesudoss, et al. "Hepatic artery Doppler indices in children with extra hepatic portal vein obstruction." Journal of clinical and experimental hepatology vol. 3,2 (2013): 102-5. doi: https://doi.org/10.1016/j.jceh.2013.04.002
Randhir J, Chandrasekaran S, Sathiyasekaran M, Venkataraman J. Hepatic artery Doppler indices in children with extra hepatic portal vein obstruction. J Clin Exp Hepatol. 2013 Jun;3(2):102-5. doi: 10.1016/j.jceh.2013.04.002. Epub 2013 Apr 29. PMID: 25755483; PMCID: PMC3940403.
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J Clin Exp Hepatol. 2013 Jun;3(2):102-5. doi: 10.1016/j.jceh.2013.04.002. Epub 2013 Apr 29.

Hepatic artery Doppler indices in children with extra hepatic portal vein obstruction.

Journal of clinical and experimental hepatology

Jesudoss Randhir, Satyabhama Chandrasekaran, Malathi Sathiyasekaran, Jayanthi Venkataraman

Affiliations

  1. Department Gastroenterology Stanley Medical College and Hospital, Chennai, India.
  2. Precision Diagnostics, Chennai, India.
  3. Paediatric Gastroenterologist, Sundaram Medical Foundation, Chennai, India.
  4. Global Health City, # 439, Cheran Nagar, Perumbakkam, Chennai 100, India ; Department of Gastroenterology, Stanley Medical College and Hospital, Chennai, India.

PMID: 25755483 PMCID: PMC3940403 DOI: 10.1016/j.jceh.2013.04.002

Abstract

UNLABELLED: Doppler measurement provides information on the hemodynamics in the hepatic artery and the portal venous system.

AIM: To study the hepatic artery hemodynamics in children with extra hepatic portal vein obstruction.

MATERIALS AND METHODS: Hepatic artery indices were studied using Doppler indices in 15 children (<12 years) with extra hepatic portal hypertension (EHPVO) and obliterated esophageal varices. The hepatic artery resistive index, the arterial acceleration time and the acceleration index were used to determine the flow pattern within the hepatic artery. Controls were 15 healthy age-sex matched children, belonging to the same socioeconomic strata in absence of liver disease.

RESULTS: The mean age of the children was 8.43 ± 3.2 years and male female ratio was 4:1. All the children had obliterated esophageal varices. The hepatic artery resistive index in the children with EHPVO was normal and similar to controls. The hepatic arterial early systolic acceleration index was significantly higher in cases compared to controls (436 ± 290 vs 214 ± 100; P value <0.004). The hepatic arterial acceleration time though low in the cases (86 ± 35 cm/s) was not statistically different from the controls (128 ± 14 cm/s).

CONCLUSION: There was a significant increase in hepatic arterial early systolic acceleration in children with chronic EHPVO. The latter may be responsible for an increase in hepatic arterial in flow velocity in a slow flow system despite a normal resistive index.

Keywords: Doppler indices; EHPVO, extra hepatic portal vein obstruction; ESA, early systolic acceleration; HAAI, hepatic artery acceleration index; HAAT, hepatic artery acceleration time; HABR, hepatic arterial buffer response; HARI, hepatic artery resistive index; RI, resistive index; extra hepatic portal venous obstruction; hepatic artery index

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