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Sinha A, Sabharwal A, Yadav N, et al. Mature cystic retroperitoneal teratoma with well differentiated renal elements: relation to spinal dysraphism. European J Pediatr Surg Rep. 2013;2(1):46-9doi: 10.1055/s-0033-1351393.
Sinha, A., Sabharwal, A., Yadav, N., Gupta, R. K., & Patir, R. (2014). Mature cystic retroperitoneal teratoma with well differentiated renal elements: relation to spinal dysraphism. European journal of pediatric surgery reports, 2(1), 46-9. https://doi.org/10.1055/s-0033-1351393
Sinha, Anand, et al. "Mature cystic retroperitoneal teratoma with well differentiated renal elements: relation to spinal dysraphism." European journal of pediatric surgery reports vol. 2,1 (2014): 46-9. doi: https://doi.org/10.1055/s-0033-1351393
Sinha A, Sabharwal A, Yadav N, Gupta RK, Patir R. Mature cystic retroperitoneal teratoma with well differentiated renal elements: relation to spinal dysraphism. European J Pediatr Surg Rep. 2014 Jun;2(1):46-9. doi: 10.1055/s-0033-1351393. Epub 2013 Aug 05. PMID: 25755970; PMCID: PMC4336057.
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European J Pediatr Surg Rep. 2014 Jun;2(1):46-9. doi: 10.1055/s-0033-1351393. Epub 2013 Aug 05.

Mature cystic retroperitoneal teratoma with well differentiated renal elements: relation to spinal dysraphism.

European journal of pediatric surgery reports

Anand Sinha, Arvind Sabharwal, Nandini Yadav, R K Gupta, Rana Patir

Affiliations

  1. Department of Pediatric Surgery, Fortis Memorial Research Institute, Gurgaon, Haryana, India.
  2. Department of Pathology, Fortis Memorial Research Institute, Gurgaon, Haryana, India.
  3. Department of Radiodiagnosis, Fortis Memorial Research Institute, Gurgaon, Haryana, India.
  4. Department of Neurosurgery, Fortis Memorial Research Institute, Gurgaon, Haryana, India.

PMID: 25755970 PMCID: PMC4336057 DOI: 10.1055/s-0033-1351393

Abstract

Retroperitoneum is a relatively uncommon site for pediatric teratomas. Rarely, such tumors can have an intraspinal extension and few cases of retroperitoneal teratomas associated with spinal dysraphism have been reported. Teratomas consist of tissues arising from all three embryonic layers. However, mature renal tissues in the form of glomeruli and tubules are sparingly found in teratomas. A 15-day-old female presented with spina bifida occulta and on evaluation a cystic presacral mass was detected. Intraoperatively the cyst was found densely adherent to the hemivertebrae but not entering the spinal canal. Histopathological examination confirmed a mature cystic teratoma but also demonstrated presence of mature renal elements in the cyst wall. The teratomas lying in proximity to spine and associated with spinal dysraphism are likely to contain mature renal tissues or even nephroblastic elements. It supports the dysembryogenic model of origin of intradural teratomas from native progenitor cells rather than aberrantly migrated germ cells.

Keywords: intraspinal extension; mature renal elements; retroperitoneal teratoma

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