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Adawiyah J, Priya G, Roshidah B. Oral antibiotics in acne vulgaris: therapeutic response over 5 years. Malays Fam Physician. 2010;5(3):130-3
Adawiyah, J., Priya, G., & Roshidah, B. (2010). Oral antibiotics in acne vulgaris: therapeutic response over 5 years. Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia, 5(3), 130-3.
Adawiyah, J, et al. "Oral antibiotics in acne vulgaris: therapeutic response over 5 years." Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia vol. 5,3 (2010): 130-3.
Adawiyah J, Priya G, Roshidah B. Oral antibiotics in acne vulgaris: therapeutic response over 5 years. Malays Fam Physician. 2010 Dec 31;5(3):130-3. eCollection 2010. PMID: 25606204; PMCID: PMC4170416.
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Malays Fam Physician. 2010 Dec 31;5(3):130-3. eCollection 2010.

Oral antibiotics in acne vulgaris: therapeutic response over 5 years.

Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia

J Adawiyah, G Priya, B Roshidah

PMID: 25606204 PMCID: PMC4170416

Abstract

INTRODUCTION: Antibiotic resistant P. acnes have influenced acne therapy worldwide resulting in increased use of topical and systemic retinoids. Judicious use of oral antibiotic is important for effective therapeutic outcome.

OBJECTIVES: To determine the response and side effects of oral antibiotic treatment in acne vulgaris. To determine the type of antibiotic used, therapy duration and the types of concomitant topical therapy.

METHODS: Retrospective analysis of the therapeutic response to oral antibiotics therapy in acne vulgaris in the Dermatology Department, Hospital Kuala Lumpur. New cases of acne vulgaris from 2005 to 2009 were randomly selected. The clinical notes of 250 patients treated with oral antibiotics were reviewed.

RESULTS: About 60% of patients achieved good to excellent response to therapy while satisfactory response was seen in 26%. Only 8% patients experienced minor side effects. Doxycycline was the most frequently prescribed antibiotic, followed by tetracycline and erythromycin ethylsuccinate. The prescribing pattern was consistent over the years. The mean duration of treatment is four to five months. Oral antibiotic was augmented with topical therapy in 98.8% of patients.

CONCLUSION: Good to excellent therapeutic response was achieved in the majority of patients and results observed have remained stable over the last five years.

Keywords: Antibiotics; acne vulgaris

References

  1. Br J Dermatol. 2003 Mar;148(3):467-78 - PubMed
  2. J Dermatolog Treat. 2005;16(4):224-8 - PubMed
  3. J Am Acad Dermatol. 2004 Jul;51(1 Suppl):S36-8 - PubMed
  4. J Am Acad Dermatol. 1991 Mar;24(3):495-500 - PubMed
  5. Acta Derm Venereol. 2002;82(2):104-7 - PubMed
  6. Br J Dermatol. 2002 May;146(5):840-8 - PubMed
  7. J Am Acad Dermatol. 2009 May;60(5 Suppl):S1-50 - PubMed
  8. J Am Acad Dermatol. 2003 Sep;49(3 Suppl):S200-10 - PubMed
  9. Lancet. 2004 Dec 18-31;364(9452):2188-95 - PubMed
  10. J Am Acad Dermatol. 2003 Sep;49(3 Suppl):S218-26 - PubMed
  11. Expert Opin Pharmacother. 2005 Mar;6(3):409-18 - PubMed
  12. J Am Acad Dermatol. 2007 Apr;56(4):651-63 - PubMed
  13. J Prim Health Care. 2009 Mar;1(1):20-5 - PubMed
  14. J Am Acad Dermatol. 1998 Aug;39(2 Pt 3):S34-7 - PubMed
  15. Semin Cutan Med Surg. 2001 Sep;20(3):139-43 - PubMed
  16. Dermatol Clin. 2009 Jan;27(1):1-15 - PubMed
  17. Am J Clin Dermatol. 2003;4(12):813-31 - PubMed
  18. Br J Dermatol. 1998 Dec;139 Suppl 53:4-8 - PubMed

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